ReviewHealthcare (Basel, Switzerland)2023
Neurological Implications of Vitamin B12 Deficiency in Diet: A Systematic Review and Meta-Analysis.
Review in Healthcare (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 9 citations in OpenAlex.
- Nutrient and Discretionary Food Intake in Vegan Adult Australians: A Cross-Sectional Study.Nutrition bulletin · 2026Article
- Clinical, demographic, and lifestyle characteristics of patients with cervicogenic headache: comparison with an age- and sex-matched group of individuals with migraine.The journal of headache and pain · 2026Article
- Association between vitamin B12 deficiency and supraventricular tachycardia: case series.Clinical nutrition research · 2026Article
- Infantile tremor syndrome: a case series from the tertiary care center of Nepal.Frontiers in nutrition · 2026Article
- Gender specific associations and interactions of fat quality with sleep and mental health in the elderly.Journal of health, population, and nutrition · 2025Article
- Methotrexate-Induced Optic Neuropathy: A Rare and Under-Recognized Cause of Visual Loss in the Elderly.Cureus · 2025Article
- The Neurological Sequelae of Vitamin B12 Deficiency: A Systematic Review and Randomized Controlled Trial.Cureus · 2025Review
- Nutritional strategies against dementia in rural populations.Frontiers in nutrition · 2025Review
- High-Folate-Low-Vitamin B12 Interaction Syndrome.European journal of case reports in internal medicine · 2025Article
- Vitamin BInternational journal of molecular sciences · 2024Review
- From OCD Symptoms to Sleep Disorders: The Crucial Role of Vitamin B12.Neuropsychiatric disease and treatment · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVitamin B12 is one of the most important B-Vitamins that the human body needs on a daily basis, the lack of which can precipitate several neurological issues.
objectivesThis systematic aimed to investigate the neurological implications of Vitamin B12 deficiency and the effects when B12 levels were corrected in susceptible individuals.
methodsThe databases PubMed-MEDLINE, Web of Science, Cochrane, and Scopus were all searched using pertinent keywords, reference searches, and citation searches. The terms used to access the database were "Cognition", "Dietary patterns", "Neurology", "Nutritional profile", and "Vitamin B12".
resultsVitamin B12 was shown to noticeably improve cognition and other neurological parameters in the short term in older adults and the short-to-medium term in children; however, there was no perceived increase/improvement when the Vitamin was administered in the longer term, either alone or in conjunction with other similar nutritional interventions.
conclusionVitamin B12's role in the improvement of neurological functions over a long-term period remains somewhat inconclusive to date, as the majority of our selected control trials did not display much correlation between the two factors. However, Vitamin B12 did improve cognition levels in both children and older adults over a short course of administration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.