Evidence map›Paper›PMID 37046814›Full record

ArticleCancers2023

Sialofucosylation Enables Platelet Binding to Myeloma Cells via P-Selectin and Suppresses NK Cell-Mediated Cytotoxicity.

Alessandro Natoni, Marina Cerreto, Maria Stefania De Propris, Maria Teresa Petrucci, Francesca Fazio, Stefania Intoppa, Maria Laura Milani, Lucy Kirkham-McCarthy, Robert Henderson, Dawn Swan and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Targeting platelet-tumor cell interactions: a novel approach to cancer therapy.Medical oncology (Northwood, London, England) · 2025
    Review
  6. Review
  7. PSGL-1 decorated with sialyl LewisScientific reports · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Alessandro NatoniHematology, Department of Translational and Precision Medicine, Sapienza University, 00161 Rome, Italy.ORCID 0000-0003-4321-9005
Marina CerretoHematology, Department of Translational and Precision Medicine, Sapienza University, 00161 Rome, Italy.ORCID 0000-0002-1554-1497
Maria Stefania De ProprisHematology, Department of Translational and Precision Medicine, Sapienza University, 00161 Rome, Italy.
Maria Teresa PetrucciHematology, Department of Translational and Precision Medicine, Sapienza University, 00161 Rome, Italy.ORCID 0000-0003-0688-4882
Francesca FazioHematology, Department of Translational and Precision Medicine, Sapienza University, 00161 Rome, Italy.
Stefania IntoppaHematology, Department of Translational and Precision Medicine, Sapienza University, 00161 Rome, Italy.
Maria Laura MilaniHematology, Department of Translational and Precision Medicine, Sapienza University, 00161 Rome, Italy.
Lucy Kirkham-McCarthyBiomedical Sciences, School of Medicine, National University of Ireland Galway, H91 TK33 Galway, Ireland.
Robert HendersonDepartment of Haematology, Galway University Hospital, H71 YR71 Galway, Ireland.
Dawn SwanDepartment of Haematology, Galway University Hospital, H71 YR71 Galway, Ireland.ORCID 0000-0003-1374-7333
Anna GuariniDepartment of Molecular Medicine, Sapienza University, 00161 Rome, Italy.
Michael O'DwyerBiomedical Sciences, School of Medicine, National University of Ireland Galway, H91 TK33 Galway, Ireland.
Robin FoàHematology, Department of Translational and Precision Medicine, Sapienza University, 00161 Rome, Italy.
Sapienza University of Rome · ITOllscoil na Gaillimhe – University of Galway · IEUniversity Hospital Galway · IE

Funding

Health Research Board CSA2012/10Italian Association for Cancer Research 21198Italian Association for Cancer Research 800924
6 · The paper itself

Abstract

Multiple myeloma (MM) is a plasma cell disorder that develops in the bone marrow (BM) and is characterized by uncontrolled proliferation and the ability to disseminate to different sites of the skeleton. Sialofucosylated structures, particularly Sialyl Lewis a/x (SLe

Indexed as

multiple myelomaNKplateletsP-selectinSLea/x

Identifiers

PMID37046814
PMCPMC10093642
OpenAlexW4362608772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.