Evidence map›Paper›PMID 37046789›Full record

ReviewCancers2023

Baicalein as Promising Anticancer Agent: A Comprehensive Analysis on Molecular Mechanisms and Therapeutic Perspectives.

A K M Helal Morshed, Supti Paul, Arafat Hossain, Tuli Basak, Md Sanower Hossain, Md Mehedi Hasan, Md Al Hasibuzzaman, Tanjim Ishraq Rahaman, Md Abdur Rashid Mia, Pollob Shing and 7 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
16.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 10 institutions in 4 countries.

A K M Helal MorshedPathology and Pathophysiology, Academy of Medical Science, Zhengzhou University, No. 100 Science Avenue, Zhengzhou 450001, China.ORCID 0000-0001-8731-5563
Supti PaulDepartment of Chemistry, University of Dhaka, Dhaka 1000, Bangladesh.
Arafat HossainBiochemistry and Molecular Biology Department, Life Science Faculty, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj 8100, Bangladesh.
Tuli BasakDepartment of Genetic Engineering and Biotechnology, Faculty of Science and Engineering, East West University, Dhaka 1212, Bangladesh.
Md Sanower HossainCentre for Sustainability of Ecosystem and Earth Resources (Pusat ALAM), Universiti Malaysia Pahang, Gambang, Kuantan 26300, Malaysia.ORCID 0000-0001-5686-2943
Md Mehedi HasanBiochemistry and Molecular Biology Department, Life Science Faculty, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj 8100, Bangladesh.
Md Al HasibuzzamanInstitute of Nutrition and Food Science, University of Dhaka, Dhaka 1000, Bangladesh.ORCID 0000-0003-0548-4836
Tanjim Ishraq RahamanDepartment of Biotechnology and Genetic Engineering, Faculty of Life Science, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj 8100, Bangladesh.ORCID 0000-0001-5225-5767
Md Abdur Rashid MiaDepartment of Pharmaceutical Technology, Faculty of Pharmacy, International Islamic University Malaysia, Kuantan 25200, Malaysia.ORCID 0000-0002-0954-4501
Pollob ShingDepartment of Genetic Engineering and Biotechnology, Faculty of Biological Science and Technology, Jashore University of Science and Technology, Jashore 7408, Bangladesh.
Md SohelDepartment of Biochemistry and Molecular Biology, Primeasia University, Banani, Dhaka 1213, Bangladesh.
Shabana BibiDepartment of Bioscience, Shifa Tameer-e-Millat University, Islamabad 44000, Pakistan.ORCID 0000-0001-9585-9042
Dipta DeyBiochemistry and Molecular Biology Department, Life Science Faculty, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj 8100, Bangladesh.ORCID 0000-0003-3037-5113
Partha BiswasLaboratory of Pharmaceutical Biotechnology and Bioinformatics, Department of Genetic Engineering and Biotechnology, Jashore University of Science and Technology, Jashore 7408, Bangladesh.ORCID 0000-0002-9766-756X
Md Nazmul HasanLaboratory of Pharmaceutical Biotechnology and Bioinformatics, Department of Genetic Engineering and Biotechnology, Jashore University of Science and Technology, Jashore 7408, Bangladesh.ORCID 0000-0002-9122-1129
Long Chiau MingSchool of Medical and Life Sciences, Sunway University, Sunway City 47500, Malaysia.ORCID 0000-0002-6971-1383
Ching Siang TanSchool of Pharmacy, KPJ Healthcare University College, Nilai 71800, Malaysia.ORCID 0000-0002-5069-3314
Gopalganj Science and Technology University · BDUniversity of Dhaka · BDEast West University · BDInternational Islamic University Malaysia · MYNilai University · MYPrimeasia University · BDShifa Tameer-e-Millat University · PKSunway University · MYUniversiti Malaysia Pahang Al-Sultan Abdullah · MYZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite significant therapeutic advancements for cancer, an atrocious global burden (for example, health and economic) and radio- and chemo-resistance limit their effectiveness and result in unfavorable health consequences. Natural compounds are generally considered safer than synthetic drugs, and their use in cancer treatment alone, or in combination with conventional therapies, is increasingly becoming accepted. Interesting outcomes from pre-clinical trials using Baicalein in combination with conventional medicines have been reported, and some of them have also undergone clinical trials in later stages. As a result, we investigated the prospects of Baicalein, a naturally occurring substance extracted from the stems of

Indexed as

angiogenesisanti-inflammatoryapoptosisautophagyBaicaleinflavonoidsnanomedicineROSsynergistic effects

Identifiers

PMID37046789
PMCPMC10093079
OpenAlexW4362580929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.