Evidence map›Paper›PMID 37046717›Full record

ArticleCancers2023

Combination of FDG PET/CT Radiomics and Clinical Parameters for Outcome Prediction in Patients with Hodgkin's Lymphoma.

Claudia Ortega, Yael Eshet, Anca Prica, Reut Anconina, Sarah Johnson, Danny Constantini, Sareh Keshavarzi, Roshini Kulanthaivelu, Ur Metser, Patrick Veit-Haibach

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  7. Texture analysis and metabolic parameters ofEuropean journal of nuclear medicine and molecular imaging · 2025
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  13. Semiquantitative 2-[Frontiers in medicine · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Claudia OrtegaJoint Department of Medical Imaging, University Health Network-Mount Sinai Hospital, Women's College Hospital, University Medical Imaging Toronto, University of Toronto, Toronto, ON M5T 1W7, Canada.
Yael EshetDepartment of Diagnostic Imaging, Chaim Sheba Medical Center, Ramat Gan 5210000, Israel.
Anca PricaDivision of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C4, Canada.
Reut AnconinaDepartment of Medical Imaging, Belilinson Hospital, Rabin Medical Center, Tel Aviv University, Petah Tikva 4941492, Israel.
Sarah JohnsonJoint Department of Medical Imaging, University Health Network-Mount Sinai Hospital, Women's College Hospital, University Medical Imaging Toronto, University of Toronto, Toronto, ON M5T 1W7, Canada.
Danny ConstantiniDepartment of Diagnostic Imaging, William Osler Health System, 2100 Bovaird Avenue East, Brampton, ON L6R 3J7, Canada.
Sareh KeshavarziBiostatistics Division, Dalla Lana School of Public Health, University of Toronto, Toronto, ON M5T 3M7, Canada.
Roshini KulanthaiveluJoint Department of Medical Imaging, University Health Network-Mount Sinai Hospital, Women's College Hospital, University Medical Imaging Toronto, University of Toronto, Toronto, ON M5T 1W7, Canada.ORCID 0000-0002-2279-8346
Ur MetserJoint Department of Medical Imaging, University Health Network-Mount Sinai Hospital, Women's College Hospital, University Medical Imaging Toronto, University of Toronto, Toronto, ON M5T 1W7, Canada.ORCID 0000-0003-3726-8994
Patrick Veit-HaibachJoint Department of Medical Imaging, University Health Network-Mount Sinai Hospital, Women's College Hospital, University Medical Imaging Toronto, University of Toronto, Toronto, ON M5T 1W7, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of the study is to evaluate the prognostic value of a joint evaluation of PET and CT radiomics combined with standard clinical parameters in patients with HL.

methodsOverall, 88 patients (42 female and 46 male) with a median age of 43.3 (range 21-85 years) were included. Textural analysis of the PET/CT images was performed using freely available software (LIFE X). 65 radiomic features (RF) were evaluated. Univariate and multivariate models were used to determine the value of clinical characteristics and FDG PET/CT radiomics in outcome prediction. In addition, a binary logistic regression model was used to determine potential predictors for radiotherapy treatment and odds ratios (OR), with 95% confidence intervals (CI) reported. Features relevant to survival outcomes were assessed using Cox proportional hazards to calculate hazard ratios with 95% CI.

resultsalbumin (

conclusionWe evaluated the value of baseline clinical parameters as well as combined PET and CT radiomics in HL patients for survival and the prediction of the need for radiotherapy treatment. We found that different combinations of all three factors/features were independently predictive of the here evaluated endpoints.

Indexed as

hodgkin lymphomaPET/CTpredictor modelsradiomics

Identifiers

PMID37046717
PMCPMC10093084

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.