Evidence map›Paper›PMID 37046705›Full record

ArticleCancers2023

Rotating Gantries Provide Individualized Beam Arrangements for Charged Particle Therapy.

Siven Chinniah, Amanda J Deisher, Michael G Herman, Jedediah E Johnson, Anita Mahajan, Robert L Foote

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Simulation and optimization of treatment schedule for multi-gantry heavy ion therapy.Technical innovations & patient support in radiation oncology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Siven ChinniahMayo Clinic Alix School of Medicine, Jacksonville, FL 32224, USA.
Amanda J DeisherDepartment of Radiation Oncology, Division of Medical Physics, Rochester, MN 55905, USA.
Michael G HermanDepartment of Radiation Oncology, Division of Medical Physics, Rochester, MN 55905, USA.
Jedediah E JohnsonDepartment of Radiation Oncology, Division of Medical Physics, Rochester, MN 55905, USA.
Anita MahajanDepartment of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Robert L FooteDepartment of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0003-3470-6872

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study evaluates beam angles used to generate highly individualized proton therapy treatment plans for patients eligible for carbon ion radiotherapy (CIRT). METHODS AND MATERIALS: We retrospectively evaluated patients treated with pencil beam scanning intensity modulated proton therapy from 2015 to 2020 who had indications for CIRT. Patients were treated with a 190° rotating gantry with a robotic patient positioning system. Treatment plans were individualized to provide maximal prescription dose delivery to the tumor target volume while sparing organs at risk. The utilized beam angles were grouped, and anatomic sites with at least 10 different beam angles were sorted into histograms.

resultsA total of 467 patients with 484 plans and 1196 unique beam angles were evaluated and characterized by anatomic treatment site and the number of beam angles utilized. The most common beam angles used were 0° and 180°. A wide range of beam angles were used in treating almost all anatomic sites. Only esophageal cancers had a predominantly unimodal grouping of beam angles. Pancreas cancers showed a modest grouping of beam angles.

conclusionsThe wide distribution of beam angles used to treat CIRT-eligible patients suggests that a rotating gantry is optimal to provide highly individualized beam arrangements.

Indexed as

carbon ion radiotherapycharged particle therapyrotating gantries

Identifiers

PMID37046705
PMCPMC10093456

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.