Evidence map›Paper›PMID 37046700›Full record

ReviewCancers2023

The Complex Cyto-Molecular Landscape of Thyroid Nodules in Pediatrics.

Davide Seminati, Stefano Ceola, Angela Ida Pincelli, Davide Leni, Andrea Gatti, Mattia Garancini, Vincenzo L'Imperio, Alessandro Cattoni, Fabio Pagni

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Evolving trends in pediatric thyroid nodules and cancer management.Annals of pediatric endocrinology & metabolism · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Davide SeminatiDepartment of Medicine and Surgery, Pathology, Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, Italy.ORCID 0000-0002-2166-301X
Stefano CeolaDepartment of Medicine and Surgery, Pathology, Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, Italy.ORCID 0000-0002-5815-987X
Angela Ida PincelliDepartment of Endocrinology, Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, Italy.
Davide LeniDepartment of Radiology, Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, Italy.
Andrea GattiDepartment of Surgery, Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, Italy.
Mattia GaranciniDepartment of Surgery, Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, Italy.
Vincenzo L'ImperioDepartment of Medicine and Surgery, Pathology, Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, Italy.ORCID 0000-0002-9284-2998
Alessandro CattoniDepartment of Pediatrics, Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, Italy.ORCID 0000-0001-6933-6723
Fabio PagniDepartment of Medicine and Surgery, Pathology, Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, Italy.ORCID 0000-0001-9625-1637
Azienda Ospedaliera San Gerardo · IT

Funding

Regione Lombardia Ricerca Finalizzata GR-2019-12368592
6 · The paper itself

Abstract

Thyroid fine-needle aspiration (FNA) is a commonly used diagnostic cytological procedure in pediatric patients for the evaluation of thyroid nodules, triaging them for the detection of thyroid cancer. In recent years, greater attention has been paid to thyroid FNA in this setting, including the use of updated ultrasound score algorithms to improve accuracy and yield, especially considering the theoretically higher risk of malignancy of these lesions compared with the adult population, as well as to minimize patient discomfort. Moreover, molecular genetic testing for thyroid disease is an expanding field of research that could aid in distinguishing benign from cancerous nodules and assist in determining their clinical management. Finally, artificial intelligence tools can help in this task by performing a comprehensive analysis of all the obtained data. These advancements have led to greater reliance on FNA as a first-line diagnostic tool for pediatric thyroid disease. This review article provides an overview of these recent developments and their impact on the diagnosis and management of thyroid nodules in children.

Indexed as

fine-needle aspirationmolecular pathologypediatricsthyroid noduleultrasound

Identifiers

PMID37046700
PMCPMC10093758
OpenAlexW4361276858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.