Evidence map›Paper›PMID 37046638›Full record

ArticleCancers2023

Prognostic Relevance and In Vitro Targeting of Concomitant PTEN and p16 Deficiency in Chordomas.

Carolin Seeling, Elena Mosca, Eva Mantel, Peter Möller, Thomas F E Barth, Kevin Mellert

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Carolin SeelingInstitute of Pathology, University Hospital of Ulm, 89081 Ulm, Germany.
Elena MoscaInstitute of Pathology, University Hospital of Ulm, 89081 Ulm, Germany.
Eva MantelInstitute of Pathology, University Hospital of Ulm, 89081 Ulm, Germany.
Peter MöllerInstitute of Pathology, University Hospital of Ulm, 89081 Ulm, Germany.
Thomas F E BarthInstitute of Pathology, University Hospital of Ulm, 89081 Ulm, Germany.
Kevin MellertInstitute of Pathology, University Hospital of Ulm, 89081 Ulm, Germany.
University Hospital Ulm · DE

Funding

Deutsche Forschungsgemeinschaft 441595227
6 · The paper itself

Abstract

Chordomas are rare bone tumors arising along the spine. Due to high resistance towards chemotherapy, surgical resection-often followed by radiation therapy-is currently the gold standard of treatment. So far, targeted systemic therapies have not been approved. The most frequent molecular alterations include the loss of

Indexed as

CDKN2Achordomap16PI3K/AKT/mTOR signalingPTEN

Identifiers

PMID37046638
PMCPMC10093147
OpenAlexW4361008816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.