Evidence map›Paper›PMID 37046627›Full record

ArticleCancers2023

Chemo-Radio-Immunotherapy for NSCLC III: ESR/ATS Thresholds for DL

Markus Stana, Brane Grambozov, Josef Karner, Isabella Gollner, Christoph Gaisberger, Elvis Ruznic, Barbara Zellinger, Raphaela Moosbrugger, Michael Studnicka, Gerd Fastner and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Markus StanaDepartment of Radiation Oncology, Paracelsus Medical University, 5020 Salzburg, Austria.ORCID 0000-0002-0155-0384
Brane GrambozovDepartment of Radiation Oncology, Paracelsus Medical University, 5020 Salzburg, Austria.
Josef KarnerDepartment of Radiation Oncology, Paracelsus Medical University, 5020 Salzburg, Austria.
Isabella GollnerDepartment of Radiation Oncology, Paracelsus Medical University, 5020 Salzburg, Austria.
Christoph GaisbergerDepartment of Radiation Oncology, Paracelsus Medical University, 5020 Salzburg, Austria.
Elvis RuznicDepartment of Radiation Oncology, Paracelsus Medical University, 5020 Salzburg, Austria.ORCID 0000-0001-7686-1008
Barbara ZellingerInstitute of Pathology, Paracelsus Medical University, 5020 Salzburg, Austria.
Raphaela MoosbruggerDepartment of Pulmonology, Paracelsus Medical University, 5020 Salzburg, Austria.
Michael StudnickaDepartment of Pulmonology, Paracelsus Medical University, 5020 Salzburg, Austria.
Gerd FastnerDepartment of Radiation Oncology, Paracelsus Medical University, 5020 Salzburg, Austria.
Felix SedlmayerDepartment of Radiation Oncology, Paracelsus Medical University, 5020 Salzburg, Austria.
Franz ZehentmayrDepartment of Radiation Oncology, Paracelsus Medical University, 5020 Salzburg, Austria.ORCID 0000-0001-5931-3907
Paracelsus Medical University · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDurvalumab following chemoradiotherapy (CRT) for non-small cell lung cancer stage III has become the standard of care (SoC) in the past few years. With this regimen, 5-year overall survival (OS) has risen to 43%. Therefore, adequate pulmonary function (PF) after treatment is paramount in long-term survivors. In this respect, carbon monoxide diffusing capacity (DL PATIENTS AND

methodsOne hundred and twelve patients with histologically confirmed NSCLC III treated between 2015/10 and 2022/03 were eligible for this study. Patients received two cycles of platinum-based induction chemotherapy followed by high-dose radiotherapy (RT). As of 2017/09, durvalumab maintenance therapy was administered for one year. The clinical endpoints were based on the thresholds jointly published by the European Respiratory Society (ERS) and the American Thoracic Society (ATS). Pre-treatment DL

resultsPatients with a pre-treatment DL

conclusionsThe current analysis revealed that DL

Indexed as

chemoradiotherapyDLCOdurvalumabESR/ATS thresholdsimmunotherapyNSCLC stage III

Identifiers

PMID37046627
PMCPMC10092995
OpenAlexW4361019081

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.