Evidence map›Paper›PMID 37046572›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Effect of Systemic Prednisone Treatment on Changes of Inflammation Markers in Chronic Rhinosinusitis.

Malgorzata Wierzchowska, Paulina Kalińczak-Górna, Magdalena Zwolińska, Joanna Ligmanowska, Justyna Durślewicz, Aleksander Zwierz, Bartosz Malinowski, Michał Wiciński, Paweł Burduk

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Malgorzata WierzchowskaDepartment of Otolaryngology, Phoniatrics and Audiology, Collegium Medicum, Nicolaus Copernicus University, 85-067 Bydgoszcz, Poland.
Paulina Kalińczak-GórnaDepartment of Otolaryngology, The Provincial Polyclinical Hospital in Toruń, 87-100 Toruń, Poland.
Magdalena ZwolińskaDepartment of Clinical Pathomorphology, Collegium Medicum, Nicolaus Copernicus University, 85-067 Bydgoszcz, Poland.
Joanna LigmanowskaDepartment of Pathophysiology, Collegium Medicum, Nicolaus Copernicus University, 85-067 Bydgoszcz, Poland.
Justyna DurślewiczDepartment of Clinical Pathomorphology, Collegium Medicum, Nicolaus Copernicus University, 85-067 Bydgoszcz, Poland.ORCID 0000-0001-7301-5324
Aleksander ZwierzDepartment of Otolaryngology, Phoniatrics and Audiology, Collegium Medicum, Nicolaus Copernicus University, 85-067 Bydgoszcz, Poland.ORCID 0000-0002-5824-8709
Bartosz MalinowskiDepartment of Pharmacology and Therapy, Collegium Medicum, Nicolaus Copernicus University, 85-067 Bydgoszcz, Poland.
Michał WicińskiDepartment of Pharmacology and Therapy, Collegium Medicum, Nicolaus Copernicus University, 85-067 Bydgoszcz, Poland.
Paweł BurdukDepartment of Otolaryngology, Phoniatrics and Audiology, Collegium Medicum, Nicolaus Copernicus University, 85-067 Bydgoszcz, Poland.ORCID 0000-0001-6653-4599

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Objective: We aimed to evaluate the effect of treatment with prednisone on nasal and systemic periostin and eotaxin expression, IgE in plasma and eosinophils in tissue. (2) Methods: We compared the values of nasal and systemic periostin, eotaxin, IgE and eosinophils in tissue in patients treated with only nasal steroids before FESS, group 1, with those treated with an oral steroid-prednisone, group 2. (3) Results: A statistically significant decrease in the level of periostin, eotaxin and IgE in plasma was achieved in patients treated with prednisone one week before and after surgery (in sequence:

Indexed as

FESSinflammationprednisonerhinosinusitissteroid

Identifiers

PMID37046572
PMCPMC10093034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.