Evidence map›Paper›PMID 37046297›Full record

ArticleBMC complementary medicine and therapies2023

Bangpungtongsung-san for patients with major depressive disorder: study protocol for a randomized controlled phase II clinical trial.

Yunna Kim, Yujin Choi, Mi Young Lee, Seung-Hun Cho, In Chul Jung, Dong-Hoon Kang, Changsop Yang

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMC complementary medicine and therapies, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yunna Kim *Department of Neuropsychiatry, College of Korean Medicine, Kyung Hee University Medical Center, Kyung Hee University, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0003-2286-1242
Yujin Choi *KM Science Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.ORCID http://orcid.org/0000-0001-5257-2340
Mi Young LeeKM Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.ORCID http://orcid.org/0000-0002-3308-340X
Seung-Hun ChoDepartment of Neuropsychiatry, College of Korean Medicine, Kyung Hee University Medical Center, Kyung Hee University, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0002-0627-768X
In Chul JungDepartment of Oriental Neuropsychiatry, College of Korean Medicine, Daejeon University, Daejeon, Republic of Korea.ORCID http://orcid.org/0000-0001-7245-4990
Dong-Hoon KangDepartment of Oriental Neuropsychiatry, College of Korean Medicine, Daejeon University, Daejeon, Republic of Korea.
Changsop YangKM Science Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea. yangunja@kiom.re.kr.ORCID http://orcid.org/0000-0003-1277-3329
Korea Institute of Oriental Medicine · KRDaejeon University · KRKyung Hee University Medical Center · KR

Funding

Korea Health Industry Development Institute HI21C2520
6 · The paper itself

Abstract

backgroundBangpungtongsung-san (BTS) is a representative herbal medicine that has been widely used for patients with obesity in east Asian countries. Various preclinical studies have demonstrated the anti-depressive effect of BTS granules in various animal models of depression. This phase II trial aimed to explore the efficacy and safety of BTS in human patients with depression.

methodsA total of 126 patients diagnosed with major depressive disorder and who are not underweight (body mass index ≥ 18.5 kg/m DISCUSSION: The results of this clinical trial will provide evidence on the efficacy and safety of BTS for patients with major depressive disorder. This study will be conducted in accordance with ethical and regulatory guidelines, and the results will be submitted and published in international peer-reviewed journals.

trial registrationCRIS registration Number: KCT0007571; registered on 2022/07/26 ( https://cris.nih.go.kr/cris/search/detailSearch.do/23192 ).

Indexed as

Drugs, Chinese HerbalMajor Depressive DisorderClinical Trials, Phase II as TopicDouble-Blind MethodEquivalence Trials as TopicHerbal MedicineHumansRandomized Controlled Trials as Topicbofu-tsusho-sanDrugs, Chinese HerbalBangpungtongseong-sanBofu-tsusho-sanClinical protocolFangfengtongsheng-sanHerbal medicineMajor depressive disorderPhase II studyRandomized controlled trial

Identifiers

PMID37046297
PMCPMC10091324
OpenAlexW4365149789

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.