ArticleBMC complementary medicine and therapies2023
Polysaccharides extracted from mulberry fruits (Morus nigra L.): antioxidant effect of ameliorating H
Article in BMC complementary medicine and therapies, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 21 citations in OpenAlex.
- Potential Involvement of Redox and Inflammatory Signalling in the Antihyperglycemic and Antioxidant Effects of Harmaline in Male Mice With Type 2 Diabetes.Endocrinology, diabetes & metabolism · 2026Article
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- Grape Seed Proanthocyanidin Extract Improves Growth Performance and Protects Against Hydrogen Peroxide-Induced Oxidative Stress to the Liver and Intestine in Weaned Hyla Rabbits.Animals : an open access journal from MDPI · 2025Article
- Impacts of Five Different Drying Methods on Volatile Organic Compounds in Mulberry Fruits.Foods (Basel, Switzerland) · 2024Article
- Contribution of Extracellular Particles Isolated fromInternational journal of molecular sciences · 2024Article
- Study of the Structure and Bioactivity of Polysaccharides from Different Parts ofMolecules (Basel, Switzerland) · 2024Article
- MulberryGenes · 2023Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
backgroundMori Fructus is an economical and readily available traditional Chinese medicine and food. Polysaccharides in Mori Fructus have clear antioxidant activity and have been found to alleviate oxidative stress (OS)-induced liver damage in experimental studies. The mechanism of regulation of cellular antioxidant activity by mulberry polysaccharides has been suggested to be Nrf2, but it is not clear whether the Nrf2 pathway is mediated by activation of other targets, and the exact process of effects in hepatocytes has yet to be elucidated.
methodsIn this study, the basic characterization of total polysaccharides extracted from mulberry fruits (Morus nigra Linn.) was analyzed. A model of oxidative damage induced by H
resultsThe results showed that a total mulberry polysaccharides (TMP) has a molecular weight of 57.5 kDa with a pyranose ring mainly composed of glucose (48.81%), galactose (22.79%) and mannose (18.2%). TMP reduced the accumulation of ROS in HepG2 cells after H
conclusionsThis study demonstrates that TMP can reduce ROS accumulation in H
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