ArticleRecent advances in anti-infective drug discovery2024
Investigation of Anti-inflammatory, Antipyretic and Analgesic Activities of
Article in Recent advances in anti-infective drug discovery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 5 citations in OpenAlex.
- Interplay of Neuroinflammation and Epilepsy in Glioblastoma Multiforme: Mechanisms and Therapeutic Implications.Journal of molecular neuroscience : MN · 2025Review
- Effects of garlic (Allium sativum L) and Citrullus colocynthis (L.) Schrad individually and in combination on male reproductive damage due to diabetes: suppression of the AGEs/RAGE/Nox-4 signaling pathway.BMC complementary medicine and therapies · 2024Article
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Authors and funding
6 authors at 3 institutions in 4 countries.
Funding
Abstract
introductionHyperpyrexia, algesia and inflammation are pathological disorders which are treated with synthetic as well as herbal medications.
aimsThe basic aim of the present study is to evaluate the ethnopharmacological activities of phytoconstituents that are present in
methodsThirty-six albino rats were used in our studies with an average weight between 150-170 g. Anti-inflammatory activity was investigated using carrageenan (an extract from a red seaweed) that induced edema in albino rat paws. However, in antipyretic and analgesic activity studies, yeast and acetic acid were used to cause pyrexia or algesia, respectively. Different doses of acetone fruit extract were used to treat inflammation, pyrexia and algesia.
resultsOur results showed that the maximum percentage inhibition of acetonic fruit extract in anti-inflammatory and analgesic activities was observed at 70% and 100%, respectively, with 400 mg/kg doses, and in pyretic activity the maximum inhibitory percentage was 86% with a 100 mg/kg dose. In
conclusionBoth
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Registered trials
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