Evidence map›Paper›PMID 37046133›Full record

ArticleActa neurologica Belgica2023

A novel scoring system for assessing adult syringomyelia associated with CM I treatment outcomes.

Jian Guan, Chenghua Yuan, Qingyu Yao, Yueqi Du, Zeyu Fang, Lei Zhang, Shanhang Jia, Can Zhang, Zhenlei Liu, Kai Wang and 6 more

3 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in Acta neurologica Belgica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06268093 phase2recruitingnot on this mapstarted 2024, after this paper: background citation

The Effect of Thalidomide in Refractory Syringomyelia(RS): a Phase II Clinical Trial

TypeinterventionalSponsorXuanwu Hospital, BeijingRan2024 to 2028Enrolled30ConditionsSyringomyelia, ThalidomideArmsThalidomide
NCT06308367 phase2recruitingnot on this mapstarted 2024, after this paper: background citation

The Effect of Betaine in Refractory Syringomyelia(RS)

TypeinterventionalSponsorXuanwu Hospital, BeijingRan2024 to 2028Enrolled30ConditionsSyringomyeliaArmsBetaine, Placebo
NCT06375759 narecruitingnot on this mapstarted 2024, after this paper: background citation

Subarachnoid-Subarachnoid (S-S) Bypass Versus Adhesion Lysis in Spinal Arachnoiditis and Syringomyelia

TypeinterventionalSponsorXuanwu Hospital, BeijingRan2024 to 2027Enrolled200ConditionsSyringomyeliaArmsSubarachnoid-Subarachnoid (S-S) Bypass, Intradural Adhesion Lysis
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Thecoperitoneal shunt placement for extensive spinal adhesive arachnoiditis or lumbosacral outlet obstruction with syringomyelia.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  3. A novel Minimally-Invasive technique for Non-Traumatic postoperative adhesive Syringomyelia.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  4. Natural history of Chiari I malformation-syringomyelia: longitudinal cohort study.Journal of neurology, neurosurgery, and psychiatry · 2025
    Article
  5. A comparative analysis of neuroendoscopic foramen magnum decompression versus traditional open surgery for Chiari Malformation Type I.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Article
  6. Article
  7. The immunopathogenesis of narcolepsy type 1.Nature reviews. Immunology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 3 countries.

Jian Guan *Department of Neurosurgery, China-INI, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Beijing, 100053, People's Republic of China.
Chenghua Yuan *Department of Neurosurgery, China-INI, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Beijing, 100053, People's Republic of China.
Qingyu YaoDepartment of Neurosurgery, China-INI, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Beijing, 100053, People's Republic of China.
Yueqi DuDepartment of Neurosurgery, China-INI, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Beijing, 100053, People's Republic of China.
Zeyu FangDepartment of Neurosurgery, China-INI, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Beijing, 100053, People's Republic of China.
Lei ZhangDepartment of Neurosurgery, China-INI, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Beijing, 100053, People's Republic of China.
Shanhang JiaDepartment of Neurosurgery, China-INI, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Beijing, 100053, People's Republic of China.
Can ZhangDepartment of Neurosurgery, China-INI, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Beijing, 100053, People's Republic of China.
Zhenlei LiuDepartment of Neurosurgery, China-INI, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Beijing, 100053, People's Republic of China.
Kai WangDepartment of Neurosurgery, China-INI, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Beijing, 100053, People's Republic of China.
Wanru DuanDepartment of Neurosurgery, China-INI, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Beijing, 100053, People's Republic of China.
Zuowei WangDepartment of Neurosurgery, China-INI, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Beijing, 100053, People's Republic of China.
Xingwen WangDepartment of Neurosurgery, China-INI, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Beijing, 100053, People's Republic of China.
Hao WuDepartment of Neurosurgery, China-INI, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Beijing, 100053, People's Republic of China.
Zan ChenDepartment of Neurosurgery, China-INI, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Beijing, 100053, People's Republic of China.
Fengzeng JianDepartment of Neurosurgery, China-INI, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Beijing, 100053, People's Republic of China. jianfengzeng@xwh.ccmu.edu.cn.ORCID http://orcid.org/0000-0001-7860-278X
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA specific scoring system for syringomyelia is lacking. Our objective was to investigate the value of a novel scoring system (Syringomyelia Outcome Scale of Xuanwu hospital, SOS-XW) in assessing surgical outcomes in the treatment of syringomyelia (SM) associated with Chiari malformation type I (CM I).

methodsA quantitative evaluation system (SOS-XW) of SM includes 4 parameters: pain (P), sensation (S), movement (M), and syringomyelia tension index (STI). The clinical data of 88 patients with CM I-related syringomyelia treated by foramen magnum and Magendie dredging (FMMD) from January 2018 to January 2019 were retrospectively analysed with a mean follow-up of 14.3 months, and the SOS-XW score was used to assess the efficacy.

resultsThe higher the SOS-XW score, the more severe was the SM and related symptoms. The mean preoperative score was 5.97, and the postoperative score was 2.66. The symptom improvement rates were 77.78% for P, 69.01% for S, 31.82% for M, and 95.06% for the syringomyelia tension index (STI). The symptom improvement rate of the PSM score was weakly correlated with the improvement rate of STI, R

conclusionsTo evaluate the surgical procedure efficacy in the treatment of syringomyelia, the SOS-XW score can provide a more objective, detailed, and comprehensive analysis, especially STI. A reduction in STI is the practical standard for assessing the effectiveness of surgery.

Indexed as

Arnold-Chiari MalformationSyringomyeliaAdultDecompression, SurgicalForamen MagnumHumansMagnetic Resonance ImagingRetrospective StudiesTreatment OutcomeChiari malformation type INatural historyScoring systemSyringomyelia

Identifiers

PMID37046133
OpenAlexW4365138123

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.