ArticleNature2023
Noncoding translation mitigation.
Open access · greenAbstract read
In one paragraph
Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.
0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
15.9field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
76 citing papers in PubMed, 103 citations in OpenAlex.
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- The long non-coding RNA-encoded microprotein MKKS3 drives colorectal cancer chemoresistance.Experimental & molecular medicine · 2026Article
- Emergence Biases in Molecular Evolution.Genome biology and evolution · 2026Review
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- Regulatory landscape of widespread stop codon readthrough inbioRxiv : the preprint server for biology · 2026Article
- Benchmarking reveals the superiority of nucleic acid foundation models in predicting lncRNA coding potential.Genome biology · 2026Article
- Sketching microprotein portraits.Protein science : a publication of the Protein Society · 2026Review
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- Human SRD5A1 as a case of gene expression indel-resistance in triple-coding region.Genome biology · 2026Article
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- Regulation of gene expression by alternative polyadenylation in health and disease.Nature reviews. Genetics · 2026Review
- Cap-adjacent 2'-O-ribose methylation of RNA in C. elegans is required for postembryonic growth and germline development in the presence of the decapping exonuclease EOL-1.Nucleic acids research · 2026Article
- Mechanism of ribosome stalling by the AMD1 C-terminal tail arrest peptide.Science advances · 2026Article
- An expanded reference catalog of translated open reading frames for biomedical research.Nucleic acids research · 2026Article
- Reactive oxygen species (ROS) in cancer: from mechanism to therapeutic implications.Signal transduction and targeted therapy · 2026Review
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- A conformation-dependent hydrophobic degron determines Rab9a-mediated vesicular trafficking.The Journal of biological chemistry · 2026Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
11 authors at 2 institutions in 1 country.
Jordan S Kesner *Cardiometabolic Genomics Program, Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.ORCID 0000-0003-1330-1980
Ziheng Chen *Cardiometabolic Genomics Program, Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.ORCID 0000-0001-5709-8529
Peiguo ShiCardiometabolic Genomics Program, Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Alexis O AparicioCardiometabolic Genomics Program, Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.ORCID 0000-0002-1107-2718
Michael R MurphyCardiometabolic Genomics Program, Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Yang GuoCardiometabolic Genomics Program, Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Aditi TrehanCardiometabolic Genomics Program, Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Jessica E LipponenTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.ORCID 0000-0002-2393-9710
Yocelyn RecinosDepartment of Systems Biology, Columbia University Irving Medical Center, New York, NY, USA.
Natura MyekuTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.
Xuebing WuCardiometabolic Genomics Program, Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA. xw2629@cumc.columbia.edu.ORCID 0000-0003-0369-5269
Columbia University Irving Medical Center · USColumbia University · US
Funding
Tumor Biology and Microenvironment ProgramP30CA013696 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Anil K Rustgi · 1985 to 2026
$115.3MThe Role of Synaptic Proteolysis in Alzheimer's Disease and Therapeutic ImplicationsR01AG064244 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MYEKU, NATURA · 2019 to 2023
$2.8MGenome-wide studies of the noncoding functions and mechanisms of human mRNAsDP2GM140977 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WU, XUEBING · 2020 to 2020
$2.4MThe Role of Immunoproteasome Function in Alzheimer's Disease and AgingRF1AG070075 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MYEKU, NATURA · 2021 to 2021
$2.3MThe Role of Immunoproteasome Function in Alzheimer's Disease and AgingR01AG070075 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MYEKU, NATURA · 2024 to 2025
$1.5MBD Biosciences InfluxS10OD020056 · OD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SNOECK, HANS-WILLEM E · 2015 to 2015
$600kBecton Dickinson LSR II Analytical Flow CytometerS10RR027050 · NCRR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CLYNES, RAPHAEL A. · 2011 to 2011
$413kNCI NIH HHS P30 CA013696NCRR NIH HHS S10 RR027050NIA NIH HHS R01 AG064244NIA NIH HHS R01 AG070075NIA NIH HHS RF1 AG070075NIGMS NIH HHS DP2 GM140977NIH HHS S10 OD020056
Abstract
Translation is pervasive outside of canonical coding regions, occurring in long noncoding RNAs, canonical untranslated regions and introns
Indexed as
Genetic CodeProtein BiosynthesisProteinsRibosomesRNA, Long NoncodingGenome, HumanHumansHydrophobic and Hydrophilic InteractionsIntronsMolecular ChaperonesPeptidesBAG6 protein, humanMolecular ChaperonesPeptidesProteinsRNA, Long Noncoding
Identifiers
What OpenQuestion holds
Textmetadata
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Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.