Evidence map›Paper›PMID 37046068›Full record

ArticleScientific reports2023

An intriguing approach toward antibacterial activity of green synthesized Rutin-templated mesoporous silica nanoparticles decorated with nanosilver.

Milad Abbasi, Razieh Gholizadeh, Seyed Reza Kasaee, Ahmad Vaez, Shreeshivadasan Chelliapan, Fouad Fadhil Al-Qaim, Issa Farhan Deyab, Mostafa Shafiee, Zahra Zareshahrabadi, Ali Mohammad Amani and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Tackling carbapenem-resistantBiotechnology notes (Amsterdam, Netherlands) · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Heliyon · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Antifungal activity of FeScientific reports · 2024
    Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Milad Abbasi *Department of Medical Nanotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran.
Razieh Gholizadeh *Department of Materials Science and Engineering, Shiraz University of Technology, Shiraz, Iran.
Seyed Reza KasaeeShiraz Endocrinology and Metabolism Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Ahmad VaezDepartment of Tissue Engineering and Applied Cell Sciences, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran.
Shreeshivadasan ChelliapanEngineering Department, Razak Faculty of Technology and Informatics, Universiti Teknologi Malaysia, Jln Sultan Yahya Petra, 54100, Kuala Lumpur, Malaysia.
Fouad Fadhil Al-QaimCollege of Science for Women, University of Babylon, Hilla, Iraq.
Issa Farhan DeyabMedical Physics Department, Al-Mustaqbal University College, Hillah, Babil, 51001, Iraq.
Mostafa ShafieeDepartment of Medical Nanotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran.
Zahra ZareshahrabadiBasic Sciences in Infectious Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Ali Mohammad AmaniDepartment of Medical Nanotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran. amani_a@sums.ac.ir.
Sareh Mosleh-ShiraziDepartment of Materials Science and Engineering, Shiraz University of Technology, Shiraz, Iran. mosleh@sutech.ac.ir.
Hesam KamyabDepartment of Biomaterials, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, 600 077, India. hesam_kamyab@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, mesoporous silica nanoparticles (MSNs) have been applied in various biomedicine fields like bioimaging, drug delivery, and antibacterial alternatives. MSNs could be manufactured through green synthetic methods as environmentally friendly and sustainable synthesis approaches, to improve physiochemical characteristics for biomedical applications. In the present research, we used Rutin (Ru) extract, a biocompatible flavonoid, as the reducing agent and nonsurfactant template for the green synthesis of Ag-decorated MSNs. Transmission electron microscopy (TEM), zeta-potential, x-ray powder diffraction (XRD), fourier transform infrared (FTIR) spectroscopy analysis, scanning electron microscopy (SEM), brunauer-emmett-teller (BET) analysis, and energy-dispersive system (EDS) spectroscopy were used to evaluate the Ag-decorated MSNs physical characteristics. The antimicrobial properties were evaluated against Staphylococcus aureus (S. aureus), Escherichia coli (E. coli), and also different types of candida. The cytotoxicity test was performed by using the MTT assay. Based on the findings, the significant antimicrobial efficacy of Ru-Ag-decorated MSNs against both gram positive and gram negative bacteria and different types of fungi was detected as well as acceptable safety and low cytotoxicity even at lower concentrations. Our results have given a straightforward and cost-effective method for fabricating biodegradable Ag-decorated MSNs. The applications of these MSNs in the domains of biomedicine appear to be promising.

Indexed as

Anti-Infective AgentsMetal NanoparticlesNanoparticlesAnti-Bacterial AgentsEscherichia coliGram-Negative BacteriaGram-Positive BacteriaMicrobial Sensitivity TestsRutinSilicon DioxideStaphylococcus aureusAnti-Bacterial AgentsAnti-Infective AgentsRutinSilicon Dioxide

Identifiers

PMID37046068
PMCPMC10097644

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.