Evidence map›Paper›PMID 37045920›Full record

ArticleNature2023

Structural basis of sensory receptor evolution in octopus.

Corey A H Allard, Guipeun Kang, Jeong Joo Kim, Wendy A Valencia-Montoya, Ryan E Hibbs, Nicholas W Bellono

Open access · greenAbstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. MolluscaGenes: A Transcriptomic Database for the Mollusca.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. A sensory system for mating in octopus.Science (New York, N.Y.) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Animal Models of Human Disease 2.0.International journal of molecular sciences · 2024
    Article
  16. Evolution of Sensory Receptors.Annual review of cell and developmental biology · 2024
    Review
  17. Review
  18. Cephalopod chemotactile sensation.Current biology : CB · 2023
    Article
  19. Article
  20. Welcome to the nursery.Nature methods · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Corey A H Allard *Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-3554-2059
Guipeun Kang *Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Jeong Joo Kim *Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Wendy A Valencia-MontoyaDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA.
Ryan E HibbsDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX, USA. rehibbs@UCSD.EDU.ORCID http://orcid.org/0000-0003-4283-1147
Nicholas W BellonoDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA. nbellono@harvard.edu.ORCID http://orcid.org/0000-0002-0829-9436
Harvard University · USThe University of Texas Southwestern Medical Center · USUniversity of California San Diego · US

Funding

Pacific Northwest Center for Cryo-EM - Screening supplementU24GM129547 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI EVANS, JAMES E, GOUAUX, JAMES E · 2018 to 2023
$54.8M
Structural basis of nicotinic acetylcholine receptor gating and toxin inhibitionR01NS120496 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI HIBBS, RYAN E · 2021 to 2025
$3.3M
Structural Basis for Sensory Receptor FunctionR01NS129060 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Nicholas Bellono, Ryan E Hibbs · 2022 to 2026
$2.9M
Molecular Mechanisms of Integrative Signal TransductionR35GM142697 · NIGMS · HARVARD UNIVERSITY · PI Nicholas Bellono · 2021 to 2026
$2.6M
Structure-function of the α4β2 nicotinic acetylcholine receptor in a lipidic environmentF32DA047848 · NIDA · UT SOUTHWESTERN MEDICAL CENTER · PI KANG, GUIPEUN · 2019 to 2021
$210k
NIDA NIH HHS F32 DA047848NIDA NIH HHS F32DA047848NIGMS NIH HHS R35 GM142697NIGMS NIH HHS U24 GM129547NIGMS NIH HHS U24GM129547NINDS NIH HHS R01 NS120496NINDS NIH HHS R01NS120496NINDS NIH HHS R01 NS129060
6 · The paper itself

Abstract

Chemotactile receptors (CRs) are a cephalopod-specific innovation that allow octopuses to explore the seafloor via 'taste by touch'

Indexed as

Evolution, MolecularOctopodiformesSensory Receptor CellsAnimalsBinding SitesCryoelectron MicroscopyHydrophobic and Hydrophilic InteractionsLigandsReceptors, NicotinicSynaptic TransmissionTouchLigandsReceptors, Nicotinic

Identifiers

PMID37045920
PMCPMC10228259
OpenAlexW4365137723

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.