Evidence map›Paper›PMID 37045585›Full record

ReviewArchives of disease in childhood2023

Emergency and perioperative management of adrenal insufficiency in children and young people: British Society for Paediatric Endocrinology and Diabetes consensus guidance.

Talat Mushtaq, Salma R Ali, Nabil Boulos, Roisin Boyle, Tim Cheetham, Justin Huw Davies, Charlotte Jane Elder, Hoong-Wei Gan, Peter C Hindmarsh, Harshini Katugampola and 7 more

Open access · hybridAbstract readReviewConsensus Statement
In one paragraph

Review in Archives of disease in childhood, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Article
  4. Neonatologists' practices in screening and managing corticosteroid-induced adrenal insufficiency in the NICU- a multicenter study.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 11 institutions in 1 country.

Talat MushtaqDepartment of Paediatric Endocrinology, Leeds Teaching Hospitals NHS Trust, Leeds, UK talat.mushtaq@nhs.net.ORCID 0000-0002-9890-7369
Salma R AliDevelopmental Endocrinology Research Group, University of Glasgow, Royal Hospital for Sick Children, Glasgow, UK.
Nabil BoulosPharmacy Department, Southampton University Hospitals NHS Trust, Southampton, UK.ORCID 0000-0002-4408-2541
Roisin BoyleDepartment of Paediatric Endocrinology, Royal Hospital for Children, Glasgow, UK.
Tim CheethamDepartment of Paediatric Endocrinology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Justin Huw DaviesDepartment of Paediatric Endocrinology, University Hospital Southampton, Southampton, UK.ORCID 0000-0001-7560-6320
Charlotte Jane ElderDepartment of Paediatric Endocrinology, Sheffield Children's Hospital NHS Foundation Trust, Sheffield, UK.ORCID 0000-0003-2390-5593
Hoong-Wei GanDepartment of Paediatric Endocrinology, Great Ormond Street Hospital for Children, London, UK.
Peter C HindmarshDevelopmental Endocrinology Research Group, University College London Hospitals, London, UK.ORCID 0000-0002-8889-3127
Harshini KatugampolaDepartment of Paediatric Endocrinology, Great Ormond Street Hospital for Children, London, UK.
Nils KroneAcademic Unit of Child Health, Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.
Maria Salomon EstebanezDepartment of Paediatric Endocrinology, Royal Manchester Children's Hospital, Manchester, UK.
Savitha ShenoyDepartment of Paediatric Endocrinology, Leicester Royal Infirmary, UHL NHS Trust, Leicester, UK.
Sally TollerfieldDepartment of Paediatric Endocrinology, Great Ormond Street Hospital for Children, London, UK.
Sze Choong WongDepartment of Paediatric Endocrinology, Royal Hospital for Children, Glasgow, UK.
Fiona ReganDepartment of Paediatric Endocrinology, Guy's and St Thomas' Hospitals NHS Trust, London, UK.
Developed by the Paediatric Adrenal Insufficiency Group on behalf of the British Society for Paediatric Endocrinology and Diabetes (BSPED)
Great Ormond Street Hospital · GBRoyal Hospital for Children · GBLeeds Teaching Hospitals NHS Trust · GBLeicester Royal Infirmary · GBNewcastle upon Tyne Hospitals NHS Foundation Trust · GBRoyal London Hospital · GBRoyal Manchester Children's Hospital · GBSheffield Children's NHS Foundation Trust · GBSt Thomas' Hospital · GBUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Sheffield · GB

Funding

Medical Research Council MR/V037757/1Medical Research Council MR/W002795/1
6 · The paper itself

Abstract

Adrenal insufficiency (AI) is characterised by lack of cortisol production from the adrenal glands. This can be a primary adrenal disorder or secondary to adrenocorticotropic hormone deficiency or suppression from exogenous glucocorticoids. Symptoms of AI in children may initially be non-specific and include growth faltering, lethargy, poor feeding, weight loss, abdominal pain, vomiting and lingering illnesses. AI is treated with replacement doses of hydrocortisone. At times of physiological stress such as illness, trauma or surgery, there is an increased requirement for exogenous glucocorticoids, which if untreated can lead to an adrenal crisis and death. There are no unified guidelines for those <18 years old in the UK, leading to substantial variation in the management of AI. This paper sets out guidance for intercurrent illness, medical, dental and surgical procedures to allow timely and appropriate recognition and treatment of AI and adrenal crisis for children and young people.

Indexed as

Adrenal InsufficiencyDiabetes MellitusAdolescentChildGlucocorticoidsHumansHydrocortisoneGlucocorticoidsHydrocortisoneEmergency Service, HospitalEndocrinologyPaediatrics

Identifiers

PMID37045585
PMCPMC10646833
OpenAlexW4365141091

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.