Evidence map›Paper›PMID 37045554›Full record

ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2023

Measurement of Cyclooxygenase Products in Plasma as Markers for Inhibition of Cyclooxygenase Isoforms by Oral Meloxicam in New Zealand White Rabbits (

Jasmine Y Sarvi, Sara M Gardhouse, Michael D Kleinhenz, Samuel E Hocker, Mikaela M Weeder, Shawnee R Montgomery, Tess A Rooney

Abstract read
In one paragraph

Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jasmine Y SarviDepartment of Clinical Sciences, Kansas State University, College of Veterinary Medicine, Manhattan, Kansas.
Sara M GardhouseDepartment of Clinical Sciences, Kansas State University, College of Veterinary Medicine, Manhattan, Kansas.
Michael D KleinhenzDepartment of Clinical Sciences, Kansas State University, College of Veterinary Medicine, Manhattan, Kansas.
Samuel E HockerDepartment of Clinical Sciences, Kansas State University, College of Veterinary Medicine, Manhattan, Kansas.
Mikaela M WeederDepartment of Clinical Sciences, Kansas State University, College of Veterinary Medicine, Manhattan, Kansas.
Shawnee R MontgomeryDepartment of Anatomy and Physiology, Kansas State University, Manhattan, Kansas.
Tess A RooneyDepartment of Clinical Sciences, Kansas State University, College of Veterinary Medicine, Manhattan, Kansas.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pain management in rabbits is a challenging task that is complicated by the rabbit's ability to hide signs of distress and the limited pharmacologic data available for this species. Pharmacokinetic data has shown that in rabbits, meloxicam, a nonsteroidal anti-inflammatory NSAID, reaches plasma concentrations that are known to provide analgesia in dogs and cats; these concentrations could theoretically alleviate pain in rabbits. However, the inhibitory effects of meloxicam on cyclooxygenase (COX) isoforms have not been studied in rabbits. In this study, we measured the products of COX-1 and COX-2 after the oral administration of a single 1 mg/kg dose of meloxicam to New Zealand White rabbits (

Indexed as

Cat DiseasesDog DiseasesThiazinesAdministration, OralAnimalsAnti-Inflammatory Agents, Non-SteroidalCatsCyclooxygenase 2DinoprostoneDogsMeloxicamPainProtein IsoformsRabbitsThiazolesAnti-Inflammatory Agents, Non-SteroidalCyclooxygenase 2DinoprostoneMeloxicamProtein IsoformsThiazinesThiazoles

Identifiers

PMID37045554
PMCPMC10230532

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.