Evidence map›Paper›PMID 37045544›Full record

Trial reportStroke and vascular neurology2023

Comparing a novel Catfish flow restoration device and the Solitaire stent retriever for thrombectomy revascularisation in emergent largevessel occlusion stroke: a prospective randomised controlled study.

Gang Luo, Xiaoyan Yan, Guodong Xiao, Liping Wei, Ya Li Kun Nai Bi Jiang, Rongyao Ma, Wenhuo Chen, Chun Fang, Zhiming Zhou, Jieqing Wan and 11 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled TrialMulticenter StudyEquivalence Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Stroke and vascular neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03820882 (Catfish Flow Restoration Device for Thrombectomy Revascularisation of Large Vessel Occlusions in Acute Ischemic Stroke), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03820882 nacompletednot on this map

Catfish Flow Restoration Device for Thrombectomy Revascularisation of Large Vessel Occlusions in Acute Ischemic Stroke: a Randomised, Parallel-group, Non-inferiority Trial

TypeinterventionalSponsorMinistry of Science and Technology of the People´s Republic of ChinaRan2019 to 2021Enrolled238ConditionsAcute Ischemic StrokeArmsCatfish, Solitaire FR
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 16 institutions in 2 countries.

Gang LuoDepartment of Intervention, Interventional Neuroradiology Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.ORCID 0000-0003-1544-1434
Xiaoyan YanBiostatistics, Peking University Clinical Research Institute, Beijing, China.
Guodong XiaoNeurology, The Second Affiliated Hospital of Suzhou University, Jiangsu, China.
Liping WeiDepartment of Neurology, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, Henan, China.
Ya Li Kun Nai Bi JiangNeurosurgery, Hotan District People's Hospital, Hotan, China.
Rongyao MaNeurology, Nanshi Hospital of Nanyang, Nanyang, China.
Wenhuo ChenNeurology, Zhangzhou Municipal Hospital of Fujian Province and Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian, China.
Chun FangDepartment of Intervention, Tongji Hospital Affiliated to Tongji University, Shanghai, Shanghai, China.
Zhiming ZhouDepartment of Intervention, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, China.
Jieqing WanDepartment of Neurosurgery, Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital, Shanghai, China.
Ya PengDepartment of Neurosurgery, Changzhou No. 1 People's Hospital, Changzhou, China.
Guilian ZhangNeurology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Junfeng ZhaoNeurology, Siping Central People's Hospital, Siping, China.
Li LiDepartment of Intervention, Xijing Hospital of Air Force Military Medical University, Xi'an, China.
Haicheng YuanNeurology, Qingdao Central Medical Group, Qingdao, China.
Jin WuNeurology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0002-9668-1490
Bing LiDepartment of Intervention, Qindao University Medical College Affiliated Yantai Yuhuangding Hospital, Yantai, Shandong, China.
Fan ZhangNeurology, Hainan General Hospital/Hainan Affiliated Hospital of Hainan Medical University, Hainan, China.
Yuhong ChengDepartment of Intervention, Linfen Central Hospital, Linfen, Shanxi, China.
Feng GaoDepartment of Intervention, Interventional Neuroradiology Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhongrong MiaoDepartment of Intervention, Interventional Neuroradiology Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China zhongrongmiao@163.com.
Capital Medical University · CNChangzhou No.2 People's Hospital · CNFirst Affiliated Hospital of Wannan Medical College · CNFujian Medical University · CNHainan General Hospital · CNLuoyang Central Hospital Affiliated to Zhengzhou University · CNNanyang Institute of Technology · CNPeking University · CNSecond Affiliated Hospital of Nanjing Medical University · CNSecond Affiliated Hospital of Xi'an Jiaotong University · CNShanghai Jiao Tong University · CNTaiping Hospital · MYTongji University · CNXian Central Hospital · CNXijing Hospital · CNYuhuangding Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Catfish stent retriever is a newly developed mechanical thrombectomy device for rapid recanalisation in emergent large vessel occlusion (ELVO) stroke. The current trial aimed to assess whether the Catfish stent retriever is non-inferior to the Solitaire stent retriever in terms of outcomes in ELVO stroke.

methodsThis was a randomised, prospective, parallel-group, multicentre, open-label, non-inferiority study conducted at 18 sites in China. The primary outcome was the proportion of cases with successful recanalisation (modified thrombolysis in cerebral infarction score of 2b or 3) following the procedure. Secondary efficacy outcomes included the National Institutes of Health Stroke Scale scores at 24 hours and 7 days or discharge if earlier, time from artery puncture to successful recanalisation and good clinical outcome (modified Rankin scale score ≤2) at 90 days. Safety outcomes included symptomatic intracranial haemorrhage, all cause-death and severe adverse events at 90 days.

resultsBetween 3 March 2019 and 5 June 2021, 118 and 120 patients were randomly allocated to the Catfish and Solitaire groups, respectively. The primary endpoint after all endovascular procedures was non-inferior in the Catfish group (88.5%, 100/113) than in the Solitaire group (87.7%, 100/114), with a rate difference (RD) of 0.78% (95% CI -7.64 to -9.20; p=0.001). Sensitivity analysis only considering the per-protocol set also yielded similar results, with an RD of 0.83% (95% CI -7.03 to -8.70; p<0.001). Additionally, the proportions of cases with good clinical outcomes (47.8% vs 50.0%, p=0.739) and all-cause death rates (17.7% vs 18.8%, p=0.700) were similar in both groups at 90 days.

conclusionsThe Catfish stent retriever is an effective and safe device for endovascular recanalisation in ELVO stroke. TRIAL REGISTRATION NUMBER: NCT03820882.

Indexed as

Arterial Occlusive DiseasesBrain IschemiaIschemic StrokeStrokeHumansProspective StudiesStentsThrombectomyTreatment OutcomeUnited StatesCerebral InfarctionClinical TrialInterventionStrokeThrombectomy

Identifiers

PMID37045544
PMCPMC10800261
OpenAlexW4365141296

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.