Evidence map›Paper›PMID 37045541›Full record

ReviewBMJ paediatrics open2023

Adenoid hypertrophy in children: a narrative review of pathogenesis and clinical relevance.

Artur Niedzielski, Lechosław Paweł Chmielik, Grażyna Mielnik-Niedzielska, Anna Kasprzyk, Joanna Bogusławska

Registry-linked trialOpen access · diamondAbstract readReview
In one paragraph

Review in BMJ paediatrics open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06674720 (Correlation of Site and Size of Adenoid Hypertrophy and Middle Ear Effusion.), which is not on this map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
14.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06674720 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Correlation of Site and Size of Adenoid Hypertrophy and Middle Ear Effusion.

Typeobservational_patient_registrySponsorAssiut UniversityRan2025 to 2027Enrolled60ConditionsAdenoid Hypertrophy, Middle Ear Effusion
3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 86 citations in OpenAlex.

  1. CD9Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Article
  3. Article
  4. Psychometric properties comparison of EQ-5D-Y-3L and CHU-9D in children with adenoid hypertrophy.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
  5. Article
  6. Multidimensional analysis of the impact of adenoid hypertrophy on pediatric dentofacial and airway structures and construction of a diagnostic model.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  7. Article
  8. Enhancing airway obstruction diagnosis with multimodal 3D shape analysis.International journal of computer assisted radiology and surgery · 2026
    Article
  9. Disrupted glutamate-gaba balance in children with adenoid hypertrophy:a targeted metabolomic and clinical correlation study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. [Pediatric burkitt lymphoma primarily involving the adenoids: a case report and literature review].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Artur NiedzielskiDepartment of Pediatric Otolaryngology, Centre of Postgraduate Medical Education, Warszawa, Poland.
Lechosław Paweł ChmielikDepartment of Pediatric Otolaryngology, Centre of Postgraduate Medical Education, Warszawa, Poland l.p.chmielik@chmielik.pl.
Grażyna Mielnik-NiedzielskaDepartment of Pediatric Otolaryngology, Medical University of Lublin, Lublin, Poland.
Anna KasprzykDepartment of Pediatric Otolaryngology, Centre of Postgraduate Medical Education, Warszawa, Poland.ORCID 0000-0001-6804-3611
Joanna BogusławskaDepartment of Biochemistry and Molecular Biology, Centre of Postgraduate Medical Education, Warszawa, Poland.ORCID 0000-0003-2568-1546
Uniwersytecki Szpital Dziecięcy · PLMedical University of Lublin · PLPostgraduate School of Molecular Medicine · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adenoids (nasopharyngeal tonsils), being part of Waldeyer's ring, are masses of lymphoid tissues located at the junction of the roof and the posterior wall of the nasopharynx. Adenoids play an important role in the development of the immune system and serve as a defence against infections, being the first organs that come into contact with respiratory and digestive antigens. The causes of adenoid hypertrophy are not fully known. They are most likely associated with aberrant immune reactions, infections, environmental exposures and hormonal or genetic factors. The aim of this review is to summarise the current knowledge of adenoid hypertrophy in children and associated diseases. Adenoid hypertrophy has many clinical manifestations that are frequent in the paediatric population and is accompanied by various comorbidities.

Indexed as

AdenoidsChildClinical RelevanceHumansHypertrophyLymphoid TissueNasopharynxAdolescent HealthAudiologyMolecular Biology

Identifiers

PMID37045541
PMCPMC10106074
OpenAlexW4365142770

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.