Evidence map›Paper›PMID 37044114›Full record

ReviewWiley interdisciplinary reviews. Nanomedicine and nanobiotechnology

Polymer nanomaterials for use as adjuvant surgical tools.

Metecan Erdi, Anthony Sandler, Peter Kofinas

Abstract readReview
In one paragraph

Review in Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Metecan ErdiDepartment of Chemical and Biomolecular Engineering, University of Maryland, College Park, Maryland, USA.ORCID 0000-0001-9267-654X
Anthony SandlerSheikh Zayed Institute for Pediatric Surgical Innovation, Joseph E. Robert Jr. Center for Surgical Care, Children's National Medical Center, Washington, DC, USA.ORCID 0000-0001-9440-2964
Peter KofinasDepartment of Chemical and Biomolecular Engineering, University of Maryland, College Park, Maryland, USA.ORCID 0000-0001-6657-3037

Funding

Sprayable Polymer Blends for Prevention of Site Specific Surgical AdhesionsR01GM141132 · NIGMS · UNIV OF MARYLAND, COLLEGE PARK · PI KOFINAS, PETER · 2022 to 2025
$1.6M
Prevention of Intraabdominal Adhesions via Release of Novel Anti-Inflammatory from Surface Eroding Polymer Solid BarrierF31DK129021 · NIDDK · UNIV OF MARYLAND, COLLEGE PARK · PI ERDI, METECAN · 2022 to 2022
$23k
NIDDK NIH HHS F31 DK129021NIGMS NIH HHS R01 GM141132
6 · The paper itself

Abstract

Materials employed in the treatment of conditions encountered in surgical and clinical practice frequently face barriers in translation to application. Shortcomings can be generalized through their reduced mechanical stability, difficulty in handling, and inability to conform or adhere to complex tissue surfaces. To overcome an amalgam of challenges, research has sought the utilization of polymer-derived nanomaterials deposited in various fashions and formulations to improve the application and outcomes of surgical and clinical interventions. Clinically prevalent applications include topical wound dressings, tissue adhesives, surgical sealants, hemostats, and adhesion barriers, all of which have displayed the potential to act as superior alternatives to current materials used in surgical procedures. In this review, emphasis will be placed not only on applications, but also on various design strategies employed in fabrication. This review is designed to provide a broad and thought-provoking understanding of nanomaterials as adjuvant tools for the assisted treatment of pathologies prevalent in surgery. This article is categorized under: Implantable Materials and Surgical Technologies > Nanomaterials and Implants Implantable Materials and Surgical Technologies > Nanoscale Tools and Techniques in Surgery.

Indexed as

Fibrin Tissue AdhesiveTissue AdhesivesAdjuvants, ImmunologicPolymersAdjuvants, ImmunologicFibrin Tissue AdhesivePolymersTissue Adhesivesadhesion barrierhemostatsurgical sealanttissue adhesivewound dressing

Identifiers

PMID37044114
PMCPMC10524211

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.