Evidence map›Paper›PMID 37043008›Full record

ArticleSurgical endoscopy2023

Propensity score-matched analysis of laparoscopic-assisted and hand-assisted laparoscopic liver resection versus pure laparoscopic liver resection: an international multicenter study.

Felix Krenzien, Moritz Schmelzle, Johann Pratschke, Nicholas L Syn, Iswanto Sucandy, Adrian K H Chiow, Marco V Marino, Mikel Gastaca, Xiaoying Wang, Jae Hoon Lee and 15 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 20 institutions in 12 countries.

Felix KrenzienDepartment of Surgery, Campus Charité Mitte and Campus Virchow-Klinikum, Charité-Universitätsmedizin, Corporate Member of Freie Universität Berlin, and Berlin Institute of Health, Berlin, Germany.
Moritz SchmelzleDepartment of Surgery, Campus Charité Mitte and Campus Virchow-Klinikum, Charité-Universitätsmedizin, Corporate Member of Freie Universität Berlin, and Berlin Institute of Health, Berlin, Germany.
Johann PratschkeDepartment of Surgery, Campus Charité Mitte and Campus Virchow-Klinikum, Charité-Universitätsmedizin, Corporate Member of Freie Universität Berlin, and Berlin Institute of Health, Berlin, Germany.
Nicholas L SynMinistry of Health Holdings and Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Iswanto SucandyAdventHealth Tampa, Digestive Health Institute, Tampa, FL, USA.
Adrian K H ChiowHepatopancreatobiliary Unit, Department of Surgery, Changi General Hospital, Singapore, Singapore.
Marco V MarinoGeneral Surgery Department, Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy.
Mikel GastacaHepatobiliary Surgery and Liver Transplantation Unit, Biocruces Bizkaia Health Research Institute, Cruces University Hospital, University of the Basque Country, Bilbao, Spain.
Xiaoying WangDepartment of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Jae Hoon LeeDepartment of Surgery, Division of Hepato-Biliary and Pancreatic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Charing C ChongDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, China.
David FuksDepartment of Digestive, Oncologic and Metabolic Surgery, Institute Mutualiste Montsouris, Universite Paris Descartes, Paris, France.
Gi Hong ChoiDivision of Hepatopancreatobiliary Surgery, Department of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Mikhail EfanovDepartment of Hepato-Pancreato-Biliary Surgery, Moscow Clinical Scientific Center, Moscow, Russia.
T Peter KinghamDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Mathieu D'HondtDepartment of Digestive and Hepatobiliary/Pancreatic Surgery, Groeninge Hospital, Kortrijk, Belgium.
Roberto I TroisiDepartment of Clinical Medicine and Surgery, Division of HPB, Minimally Invasive and Robotic Surgery, Federico II University Hospital Naples, Naples, Italy.
Sung Hoon ChoiDepartment of General Surgery, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea.
Robert P SutcliffeDepartment of Hepatopancreatobiliary and Liver Transplant Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Rong LiuFaculty of Hepatopancreatobiliary Surgery, The First Medical Center of Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Tan-To CheungDepartment of Surgery, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.
Chung Ngai TangDepartment of Surgery, Pamela Youde Nethersole Eastern Hospital, Hong Kong SAR, China.
Ho-Seong HanDepartment of Surgery, Seoul National University Hospital Bundang, Seoul National University College of Medicine, Seoul, Korea.
Brian K P GohDepartment of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital and National Cancer Centre Singapore, Level 5, 20 College Road, Academia, Singapore, 169856, Singapore. bsgkp@hotmail.com.ORCID 0000-0001-8218-4576
International robotic and laparoscopic liver resection study group investigators
Berlin Institute of Health at Charité - Universitätsmedizin Berlin · DEUlsan College · KRChinese PLA General Hospital · CNFederico II University Hospital · ITUniversity of the Basque Country · ESAdventHealth Tampa · USAZ Groeninge · BEChangi General Hospital · SGCHA University Bundang Medical Center · KRChinese University of Hong Kong · HKFudan University · CNMemorial Sloan Kettering Cancer Center · USMinistry of Health · SGMoscow Clinical Scientific Center · RUNational University of Singapore · SGOspedale Vincenzo Cervello · ITPamela Youde Nethersole Eastern Hospital · CNQueen Mary Hospital · CNSeoul National University Hospital · KRUniversité Paris Cité · FR

Funding

US National Cancer Institute MSKCC Core Grant P30 CA008747
6 · The paper itself

Abstract

backgroundLaparoscopic-assisted (LALR) and hand-assisted (HALR) liver resections have been utilized during the early adoption phase by surgeons when transitioning from open surgery to pure LLR. To date, there are limited data reporting on the outcomes of LALR or HALR compared to LLR. The objective was to compare the perioperative outcomes after LALR and HALR versus pure LLR.

methodsThis is an international multicentric analysis of 6609 patients undergoing minimal-invasive liver resection at 21 centers between 2004 and 2019. Perioperative outcomes were analyzed after propensity score matching (PSM) comparison between LALR and HALR versus LLR.

results5279 cases met study criteria of whom 5033 underwent LLR (95.3%), 146 underwent LALR (2.8%) and 100 underwent HALR (1.9%). After 1:4 PSM, LALR was associated with inferior outcomes as evidenced by the longer postoperative stay, higher readmission rate, higher major morbidity rate and higher in-hospital mortality rate. Similarly, 1:6 PSM comparison between HALR and LLR also demonstrated poorer outcomes associated with HALR as demonstrated by the higher open conversion rate and higher blood transfusion rate. All 3 approaches technical variants demonstrated the same oncological radicality (R1 rate).

conclusionLALR and HALR performed during the learning curve was associated with inferior perioperative outcomes compared to pure LLR.

Indexed as

Carcinoma, HepatocellularHand-Assisted LaparoscopyLaparoscopyLiver NeoplasmsHepatectomyHumansLength of StayPostoperative ComplicationsPropensity ScoreRetrospective StudiesHand-assistedHybridLaparoscopic-assistedLaparoscopic liver resectionLiverMinimal-invasiveOncology

Identifiers

PMID37043008
OpenAlexW4365135410

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.