SynthesisEuropean radiology2023
Magnetic resonance imaging of the knee for chronological age estimation-a systematic review.
Synthesis in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 11 citations in OpenAlex.
- Dual-input deep learning bone age assessment in late adolescence using hand and knee radiographs.Skeletal radiology · 2026Article
- MRI-based cervical ring apophysis maturation: a probabilistic approach to legal age thresholds.International journal of legal medicine · 2026Article
- Forensic Age Estimation of the Knee with 3D MEDIC MRI.Diagnostics (Basel, Switzerland) · 2026Article
- Therapeutic progress in the management of triplane fractures in adolescents.Frontiers in pediatrics · 2026Review
- Forensic age estimation using Vieth classification in adolescents of northern China based on the knee MRI.International journal of legal medicine · 2025Article
- Application of Vieth staging in forensic age estimation in the living using MRI of the distal radial epiphysis.International journal of legal medicine · 2025Article
- T2-weighted spoiled gradient echo MRI for forensic age estimation: a study on knee growth plates.International journal of legal medicine · 2025Article
- Forensic age estimation by MRI of the knee - comparison of two classifications for ossification stages in a German population.International journal of legal medicine · 2024Article
- Bone Age Determination of Epiphyseal Fusion at Knee Joint and Its Correlation with Chronological Age.Medicina (Kaunas, Lithuania) · 2024Article
- Improving the Age Estimation Efficiency by Calculation of the Area Ratio Index Using Semi-Automatic Segmentation of Knee MRI Images.Biomedicines · 2023Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionRadiographs of the hand and teeth are frequently used for medical age assessment, as skeletal and dental maturation correlates with chronological age. These methods have been criticized for their lack of precision, and magnetic resonance imaging (MRI) of the knee has been proposed as a more accurate method. The aim of this systematic review is to explore the scientific and statistical evidence for medical age estimation based on skeletal maturation as assessed by MRI of the knee. MATERIALS AND
methodsA systematic review was conducted that included studies published before April 2021 on living individuals between 8 and 30 years old, with presumptively healthy knees for whom the ossification stages had been evaluated using MRI. The correlation between "mature knee" and chronological age and the risk of misclassifying a child as an adult and vice versa was calculated.
resultsWe found a considerable heterogeneity in the published studies -in terms of study population, MRI protocols, and grading systems used. There is a wide variation in the correlation between maturation stage and chronological age.
conclusionData from published literature is deemed too heterogenous to support the use of MRI of the knee for chronological age determination. Further, it is not possible to assess the sensitivity, specificity, negative predictive value, or positive predictive value for the ability of MRI to determine whether a person is over or under 18 years old. KEY POINTS: • There is an insufficient scientific basis for the use of magnetic resonance imaging of the knee in age determination by skeleton. • It is not possible to assess the predictive value of MRI of the knee to determine whether a person is over or under 18 years of age.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.