Evidence map›Paper›PMID 37041537›Full record

ArticleJournal of nanobiotechnology2023

Cascade amplification of tumor chemodynamic therapy and starvation with re-educated TAMs via Fe-MOF based functional nanosystem.

Xinmin Zheng, Xiang Li, Siyu Meng, Guolin Shi, Hui Li, Huiping Du, Liangliang Dai, Hui Yang

Open access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Concave-Octahedral FeGels (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Iron-MOFs for Biomedical Applications.Advanced healthcare materials · 2025
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xinmin ZhengSchool of Life Sciences, Northwestern Polytechnical University, Xi'an, 710072, China.
Xiang LiSchool of Life Sciences, Northwestern Polytechnical University, Xi'an, 710072, China.
Siyu MengInstitute of Medical Research, Northwestern Polytechnical University, Xi'an, 710072, China.
Guolin ShiSchool of Life Sciences, Northwestern Polytechnical University, Xi'an, 710072, China.
Hui LiSchool of Life Sciences, Northwestern Polytechnical University, Xi'an, 710072, China.
Huiping DuInstitute of Medical Research, Northwestern Polytechnical University, Xi'an, 710072, China.
Liangliang DaiInstitute of Medical Research, Northwestern Polytechnical University, Xi'an, 710072, China. liangliangdai@nwpu.edu.cn.
Hui YangSchool of Life Sciences, Northwestern Polytechnical University, Xi'an, 710072, China. kittyyh@163.com.
Northwestern Polytechnical University · CN

Funding

Fundamental Research Funds for the Central Universities D5000220120Key R & D Program of Shaanxi Province 2022SF-012National Natural Science Foundation of China 52003223Young Talent fund of University Association for Science and Technology in Shaanxi 20200302
6 · The paper itself

Abstract

Tumor microenvironment is characterized by the high concentration of reactive oxygen species (ROS), which is an effective key used to open the Pandora's Box against cancer. Herein, a tumor-targeted nanosystem HFNP@GOX@PFC composed of ROS-cleaved Fe-based metal-organic framework, hyaluronic acid (HA), glucose oxidase (GOX) and perfluorohexane (PFC) has been developed for tumor cascade amplified starvation and chemodynamic therapy (CDT). In response to the high concentration of hydrogen peroxide (H

Indexed as

StarvationTumor-Associated MacrophagesEndocytosisGlucoseGlucose OxidaseHumansHydrogen PeroxideReactive Oxygen SpeciesGlucoseGlucose OxidaseHydrogen PeroxideReactive Oxygen SpeciesCascade amplificationChemodynamic therapyFe-Mof nanosystemRe-education macrophagesTumor starvation

Identifiers

PMID37041537
PMCPMC10088258
OpenAlexW4364377961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.