Evidence map›Paper›PMID 37041376›Full record

ArticleThe AAPS journal2023

Plasma Stability and Plasma Metabolite Concentration-Time Profiles of Oligo(Lactic Acid)

Lauren Repp, Sarah L Skoczen, Morteza Rasoulianboroujeni, Stephan T Stern, Glen S Kwon

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The AAPS journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Crystallization of supersaturated PEG-b-PLA for the production of drug-loaded polymeric micelles.Journal of controlled release : official journal of the Controlled Release Society · 2025
    Article
  3. Recent Advances in Drug Delivery.The AAPS journal · 2024
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lauren ReppPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin, Madison, Wisconsin, 53705, USA.
Sarah L SkoczenNanotechnology Characterization Laboratory, Cancer Research Technology Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research Sponsored By the National Cancer Institute, Frederick, Maryland, 21702, USA.
Morteza RasoulianboroujeniPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin, Madison, Wisconsin, 53705, USA.
Stephan T SternNanotechnology Characterization Laboratory, Cancer Research Technology Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research Sponsored By the National Cancer Institute, Frederick, Maryland, 21702, USA.
Glen S KwonPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin, Madison, Wisconsin, 53705, USA. glen.kwon@wisc.edu.
University of Wisconsin–Madison · USLeidos (United States) · USNational Cancer Institute · US

Funding

WORK ORDER 126643 B539 EXPAND IC SUITE75N91019D00024 · NIAID · LEIDOS BIOMEDICAL RESEARCH, INC. · PI BRISCOE, LYNN · 2019 to 2025
$3932.6M
Oligo(lactic acid)n-Prodrug Nanomedicines for Combination TherapyR01CA257837 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI KWON, GLEN S. · 2021 to 2024
$1.4M
NCI NIH HHS 75N91019D00024NCI NIH HHS R01 CA257837
6 · The paper itself

Abstract

Paclitaxel (PTX) is a frequently prescribed chemotherapy drug used to treat a wide variety of solid tumors. Oligo(lactic acid)

Indexed as

PaclitaxelProdrugsAlbumin-Bound PaclitaxelAnimalsCell Line, TumorDrug CarriersHumansLactic AcidMiceMicellesPolyestersPolyethylene GlycolsPolymersRatsRats, Sprague-DawleyAlbumin-Bound PaclitaxelDrug CarriersLactic AcidMicellesmonomethoxypolyethyleneglycol-polylactide block copolymerPaclitaxelPolyestersPolyethylene GlycolsPolymersProdrugsmetabolitepaclitaxelpolymeric micelleprodrug

Identifiers

PMID37041376
PMCPMC10141660
OpenAlexW4364376140

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.