Evidence map›Paper›PMID 37041124›Full record

ArticleACS applied materials & interfaces2023

Nitrilotriacetic Acid Improves Plasma Electrolytic Oxidation of Titanium for Biomedical Applications.

Sergiy Kyrylenko, Maciej Sowa, Alicja Kazek-Kęsik, Agnieszka Stolarczyk, Marcin Pisarek, Yevheniia Husak, Viktoriia Korniienko, Volodymyr Deineka, Roman Moskalenko, Izabela Matuła and 5 more

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Article in ACS applied materials & interfaces, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Sergiy KyrylenkoBiomedical Research Center, Sumy State University, 31 Sanatorna Street, Sumy 40018, Ukraine.ORCID 0000-0002-4343-0065
Maciej SowaFaculty of Chemistry, Silesian University of Technology, 6 B. Krzywoustego Street, 44-100 Gliwice, Poland.
Alicja Kazek-KęsikFaculty of Chemistry, Silesian University of Technology, 6 B. Krzywoustego Street, 44-100 Gliwice, Poland.ORCID 0000-0001-9971-7279
Agnieszka StolarczykFaculty of Chemistry, Silesian University of Technology, 6 B. Krzywoustego Street, 44-100 Gliwice, Poland.ORCID 0000-0001-9594-9072
Marcin PisarekInstitute of Physical Chemistry PAS, M. Kasprzaka Street 44/52, 01-224 Warsaw, Poland.ORCID 0000-0002-7424-5954
Yevheniia HusakBiomedical Research Center, Sumy State University, 31 Sanatorna Street, Sumy 40018, Ukraine.
Viktoriia KorniienkoBiomedical Research Center, Sumy State University, 31 Sanatorna Street, Sumy 40018, Ukraine.
Volodymyr DeinekaBiomedical Research Center, Sumy State University, 31 Sanatorna Street, Sumy 40018, Ukraine.ORCID 0000-0002-9492-8170
Roman MoskalenkoUkrainian-Swedish Research Center SUMEYA, Sumy State University, 31 Pryvokzalna Street, Sumy 40018, Ukraine.ORCID 0000-0002-2342-0337
Izabela MatułaFaculty of Science and Technology, Institute of Materials Engineering, University of Silesia, 75 Pułku Piechoty Street 1a, 41-500 Chorzów, Poland.
Joanna MichalskaFaculty of Chemistry, Silesian University of Technology, 6 B. Krzywoustego Street, 44-100 Gliwice, Poland.
Agata Jakóbik-KolonFaculty of Chemistry, Silesian University of Technology, 6 B. Krzywoustego Street, 44-100 Gliwice, Poland.
Oleg MishchenkoNano Prime LTD, 25 Metalowców Street, 39-200 Dębica, Poland.
Maksym PogorielovBiomedical Research Center, Sumy State University, 31 Sanatorna Street, Sumy 40018, Ukraine.ORCID 0000-0001-9372-7791
Wojciech SimkaFaculty of Chemistry, Silesian University of Technology, 6 B. Krzywoustego Street, 44-100 Gliwice, Poland.ORCID 0000-0002-2648-5523
Silesian University of Technology · PLSumy State University · UAInstitute of Physical Chemistry · PLUniversity of Silesia in Katowice · PLZaporizhzhia State Medical and Pharmaceutical University · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dental implants have become a routine, affordable, and highly reliable technology to replace tooth loss. In this regard, titanium and its alloys are the metals of choice for the manufacture of dental implants because they are chemically inert and biocompatible. However, for special cohorts of patients, there is still a need for improvements, specifically to increase the ability of implants to integrate into the bone and gum tissues and to prevent bacterial infections that can subsequently lead to peri-implantitis and implant failures. Therefore, titanium implants require sophisticated approaches to improve their postoperative healing and long-term stability. Such treatments range from sandblasting to calcium phosphate coating, fluoride application, ultraviolet irradiation, and anodization to increase the bioactivity of the surface. Plasma electrolytic oxidation (PEO) has gained popularity as a method for modifying metal surfaces and delivering the desired mechanical and chemical properties. The outcome of PEO treatment depends on the electrochemical parameters and composition of the bath electrolyte. In this study, we investigated how complexing agents affect the PEO surfaces and found that nitrilotriacetic acid (NTA) can be used to develop efficient PEO protocols. The PEO surfaces generated with NTA in combination with sources of calcium and phosphorus were shown to increase the corrosion resistance of the titanium substrate. They also support cell proliferation and reduce bacterial colonization and, hence, lead to a reduction in failed implants and repeated surgeries. Moreover, NTA is an ecologically favorable chelating agent. These features are necessary for the biomedical industry to be able to contribute to the sustainability of the public healthcare system. Therefore, NTA is proposed to be used as a component of the PEO bath electrolyte to obtain bioactive surface layers with properties desired for next-generation dental implants.

Indexed as

Dental ImplantsTitaniumAlloysCoated Materials, BiocompatibleElectrolytesHumansMetalsNitrilotriacetic AcidOxidation-ReductionSurface PropertiesAlloysCoated Materials, BiocompatibleDental ImplantsElectrolytesMetalsNitrilotriacetic AcidTitaniumbiocompatibilitycomplexing agentcorrosion resistancedental implantplasma electrolytic oxidationsurface processing

Identifiers

PMID37041124
PMCPMC10141263
OpenAlexW4365135720

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.