Evidence map›Paper›PMID 37041081›Full record

Observational studyNeurology2023

Outcomes in Patients With COVID-19 With Acute Encephalopathy and Coma: An International Prospective Study.

Stephane Legriel, Rafael Badenes, Nicolas Engrand, Rocio Mendoza-Trujillo, Pauline Soulier, Sarah Benghanem, Michael Pizzi, Carolina Maciel, Jonathan Chelly, Benjamin Zuber and 33 more

Registry-linked trialOpen access · greenAbstract readObservational Study
In one paragraph

Observational study in Neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04320472 (Outcomes in Patients With Acute Encephalopathy and SARS-Cov-2 Infection), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04320472 unknown statusnot on this map

Outcomes in Patients With Acute Encephalopathy and SARS-Cov-2 Infection

Typeobservational_patient_registrySponsorIctal GroupRan2020 to 2020Enrolled250ConditionsCOVID-19, Encephalopathy, Critically IllArmsFollow up
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

43 authors at 3 institutions in 2 countries.

Stephane LegrielFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil. stephane.legriel@ictalgroup.org.ORCID 0000-0003-4782-6734
Rafael BadenesFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0001-7017-0150
Nicolas EngrandFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.
Rocio Mendoza-TrujilloFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.
Pauline SoulierFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.
Sarah BenghanemFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0003-2544-0291
Michael PizziFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.
Carolina MacielFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.
Jonathan ChellyFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0002-8198-1239
Benjamin ZuberFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0003-4030-5311
Marie LabruyereFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0002-0541-7564
Gaetan PlantefeveFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.
Gwenaëlle JacqFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0003-2927-9570
Arnaud GalboisFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0002-2516-8358
Yoann LauneyFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0001-9105-8862
Laurent ArgaudFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0002-4565-2454
Olivier LesieurFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0001-9135-2041
Alexis FerreFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0002-5752-8274
Marine PaulFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0002-0717-9555
Antoine GuillonFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0002-4884-8620
Pierre BaillyFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.
Pascal BeuretFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0003-4870-0076
Marie-Charlotte de-CarneFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.
Shidasp SiamiFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0002-0828-8403
Dalila BenzekriFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.
Gwenhael ColinFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0001-7607-9913
Leidy GaviriaFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.
Jose Luis AldanaFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0002-6358-8329
Cedric BruelFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0001-8895-6370
Annabelle StoclinFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0003-0052-3103
Nicholas SedillotFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.
Guillaume GeriFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0002-7691-6635
Daniel SamanoFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.
Evie SobczakFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.
Emily SwaffordFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0002-9137-7895
Kristine O'PhelanFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.
Arnaud MeffertFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0003-3632-3277
Mathilde HollevilleFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0001-6605-4202
Stein SilvaFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.
Manoel José Alves da CostaFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.
Jorge MejiaFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.
Ayham AlkhachroumFrom the Intensive Care Unit (S.L., G.J., A.F., M. Paul, M.-C.d.-C.), Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay; University Paris-Saclay (S.L., G.J.), UVSQ, INSERM, CESP, Team « PsyDev », Villejuif; IctalGroup (S.L., P.S., J.C., M.L., G.P., G.J., A. Galbois, O.L., P. Bailly, P. Beuret, C.B., A.S., A.M.), Le Chesnay, France; Anesthesiology and Surgical-Trauma Intensive Care (R.B.), University Clinic Hospital, Valencia; Department of Surgery (R.B.), University of Valencia, Spain; Neuro-Intensive Care Unit (N.E.), Rothschild Foundation Hospital, Paris, France; Anesthesiology and Intensive Care (R.M.-T.), Hospital Regional de Alta Especilidad del Bajío, Leon, Mexico; Intensive Care Unit (P.S.), Groupe Hospitalier Sud Ile de France, Melun; Medical ICU (S.B.), Cochin Hospital, AP-HP, Paris, France; Departments of Neurology and Neurosurgery (M. Pizzi, C.M.), University of Florida College of Medicine, Gainesville; Department of Neurology (C.M.), Yale University School of Medicine, New Haven, CT; Department of Neurology (C.M.), University of Utah, Salt Lake City; Intensive Care Unit (J.C.), Centre Hospitalier Intercommunal Toulon La Seyne sur Mer; Intensive Care Unit (B.Z.), Hôpital Foch, Suresnes; Réanimation Médicale (M.L.), CHU Dijon; Service de Médecine Intensive Réanimation (G.P.), Centre Hospitalier d'Argenteuil; Intensive Care Unit (A. Galbois), Claude Galien Private Hospital, Quincy-sous-Senart, Île-de-France; Réanimation Chirurgicale (Y.L.), Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Rennes; Hospices Civils de Lyon (L.A.), Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation; Université de Lyon (L.A.), Université Claude Bernard Lyon 1, Faculté de Médecine Lyon-Est; Service de Réanimation (O.L.), Centre Hospitalier de la Rochelle, Nouvelle-Aquitaine; Intensive Care Unit (A. Guillon), Tours University Hospital; INSERM UMR 1100 (Research Center for Respiratory Diseases) (A. Guillon), University of Tours; Médecine Intensive Réanimation (P. Bailly), CHU de Brest; Service de Réanimation et Soins Continus (P. Beuret), Centre Hospitalier de Roanne, Rhône-Alpes; Polyvalent ICU (S. Siami), Centre Hospitalier Sud Essonne Dourdan-Etampes, Paris; Médecine Intensive Réanimation (D.B.), Centre Hospitalier Régional d'Orléans; Médecine Intensive Réanimation (G.C.), District Hospital Center, La Roche-sur-Yon, France; Centro de Investigación Clínica (L.G.), and Adult Intensive Care Unit (J.L.A., J.M.), Fundación Valle del Lili, University Hospital, Cali, Colombia; Service de Réanimation (C.B.), Groupe Hospitalier Paris Saint Joseph; Service de Réanimation (A.S.), Institut Gustave Roussy, Villejuif, France; Service de Réanimation (N.S.), Hôpital Fleyriat, Bourg en Bresse; Service de Médecine Intensive Réanimation (G.G.), Hôpital Universitaire Ambroise-Paré, APHP, Boulogne-Billancourt, France; Department of Neurology (D.S., Evie Sobczak, Emily Swafford, K.O.P., A.A.), University of Miami, FL; Service d'Anesthésie Réanimation Chirurgicale (A.M.), Hôpital Henri Mondor, Creteil, Île-de-France; Department of Anesthesiology and Critical Care (M.H.), Beaujon Hospital, DMU Parabol, AP-HP. Nord, Paris; Critical Care Unit (S. Silva), University Teaching Hospital of Purpan, Toulouse Cedex 9; Toulouse NeuroImaging Center (S. Silva), Toulouse University, UMR INSERM/UPS 1214, UPS, France; and Intensive Care Unit (M.J.A.d.C.), Hospital Nossa Senhora de Lourdes (Antigo Hospital Alfa), Recife, Pernambuco, Brazil.ORCID 0000-0003-0352-5913
for NeuroCovid19
Inserm · FRFondation de Rothschild · FRUniversité Toulouse III - Paul Sabatier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesTo report the prevalence of acute encephalopathy and outcomes in patients with severe coronavirus disease 2019 (COVID-19) and to identify determinants of 90-day outcomes.

methodsData from adults with severe COVID-19 and acute encephalopathy were prospectively collected for patients requiring intensive care unit management in 31 university or university-affiliated intensive care units in 6 countries (France, United States, Colombia, Spain, Mexico, and Brazil) between March and September of 2020. Acute encephalopathy was defined, as recently recommended, as subsyndromal delirium or delirium or as a comatose state in case of severely decreased level of consciousness. Logistic multivariable regression was performed to identify factors associated with 90-day outcomes. A Glasgow Outcome Scale-Extended (GOS-E) score of 1-4 was considered a poor outcome (indicating death, vegetative state, or severe disability).

resultsOf 4,060 patients admitted with COVID-19, 374 (9.2%) experienced acute encephalopathy at or before the intensive care unit (ICU) admission. A total of 199/345 (57.7%) patients had a poor outcome at 90-day follow-up as evaluated by the GOS-E (29 patients were lost to follow-up). On multivariable analysis, age older than 70 years (odds ratio [OR] 4.01, 95% CI 2.25-7.15), presumed fatal comorbidity (OR 3.98, 95% CI 1.68-9.44), Glasgow coma scale score <9 before/at ICU admission (OR 2.20, 95% CI 1.22-3.98), vasopressor/inotrope support during ICU stay (OR 3.91, 95% CI 1.97-7.76), renal replacement therapy during ICU stay (OR 2.31, 95% CI 1.21-4.50), and CNS ischemic or hemorrhagic complications as acute encephalopathy etiology (OR 3.22, 95% CI 1.41-7.82) were independently associated with higher odds of poor 90-day outcome. Status epilepticus, posterior reversible encephalopathy syndrome, and reversible cerebral vasoconstriction syndrome were associated with lower odds of poor 90-day outcome (OR 0.15, 95% CI 0.03-0.83). DISCUSSION: In this observational study, we found a low prevalence of acute encephalopathy at ICU admission in patients with COVID-19. More than half of patients with COVID-19 presenting with acute encephalopathy had poor outcomes as evaluated by GOS-E. Determinants of poor 90-day outcome were dominated by older age, comorbidities, degree of impairment of consciousness before/at ICU admission, association with other organ failures, and acute encephalopathy etiology. TRIAL REGISTRATION INFORMATION: The study is registered with ClinicalTrials.gov, number NCT04320472.

Indexed as

COVID-19DeliriumPosterior Leukoencephalopathy SyndromeAdultAgedComaHumansIntensive Care UnitsProspective Studies

Identifiers

PMID37041081
PMCPMC10259271
OpenAlexW4364356163

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