Evidence map›Paper›PMID 37041022›Full record

ReviewInternational journal of gynecological cancer : official journal of the International Gynecological Cancer Society2023

Improvement in radiation techniques for locally advanced cervical cancer during the last two decades.

Satoru Sagae, Takafumi Toita, Motoki Matsuura, Manabu Saito, Takuma Matsuda, Nanaka Sato, Ayumi Shimizu, Toshiaki Endo, Miho Fujii, David K Gaffney and 1 more

Open access · hybridAbstract readReview
In one paragraph

Review in International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Satoru SagaeWomen's Medical Center, Tokeidai Memorial Hospital, Sapporo, Hokkaido, Japan str-sagae@outlook.jp.ORCID 0000-0002-1802-1569
Takafumi ToitaRadiation Therapy Center, Okinawa Chubu Hospital, Uruma, Okinawa, Japan.ORCID 0000-0003-3907-0228
Motoki MatsuuraDepartment of Obstetrics and Gynecology, Sapporo Medical University, Sapporo, Hokkaido, Japan.ORCID 0000-0002-6589-6480
Manabu SaitoWomen's Medical Center, Tokeidai Memorial Hospital, Sapporo, Hokkaido, Japan.
Takuma MatsudaWomen's Medical Center, Tokeidai Memorial Hospital, Sapporo, Hokkaido, Japan.
Nanaka SatoWomen's Medical Center, Tokeidai Memorial Hospital, Sapporo, Hokkaido, Japan.
Ayumi ShimizuWomen's Medical Center, Tokeidai Memorial Hospital, Sapporo, Hokkaido, Japan.
Toshiaki EndoWomen's Medical Center, Tokeidai Memorial Hospital, Sapporo, Hokkaido, Japan.
Miho FujiiWomen's Medical Center, Tokeidai Memorial Hospital, Sapporo, Hokkaido, Japan.ORCID 0000-0002-0785-2578
David K GaffneyDepartment of Radiation Oncology, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0002-5752-1611
William SmallDepartment of Radiation Oncology, Loyola University Chicago, Stritch School of Medicine, Cardinal Bernardin Cancer Center, Maywood, Illinois, USA.ORCID 0000-0002-1623-9863
Tokeidai Memorial Hospital · JPSapporo Medical University · JPAdvanced Radiation Therapy (United States) · USLoyola University Chicago · USUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the National Cancer Institute (NCI) alert of concurrent chemoradiotherapy, radiotherapy has been changed from external beam radiotherapy plus brachytherapy to platinum-based concurrent chemoradiotherapy. Therefore, concurrent chemoradiotherapy plus brachytherapy has become a standard treatment for locally advanced cervical cancer. Simultaneously, definitive radiotherapy has been changed gradually from external beam radiotherapy plus low-dose-rate intracavitary brachytherapy to external beam radiotherapy plus high-dose-rate intracavitary brachytherapy. Cervix cancer is uncommon in developed countries; hence, international collaborations have been critical in large-scale clinical trials. The Cervical Cancer Research Network (CCRN), created from the Gynecologic Cancer InterGroup (GCIG), has investigated various concurrent chemotherapy regimens and sequential methods of radiation and chemotherapy. Most recently, many clinical trials of combining immune checkpoint inhibitors with radiotherapy have been ongoing for sequential or concurrent settings. During the last decade, the method of standard radiation therapy has changed from three-dimensional conformal radiation therapy to intensity-modulated radiation therapy for external beam radiotherapy and from two-dimensional to three-dimensional image-guided approaches for brachytherapy. Recent improvements include stereotactic ablative body radiotherapy and MRI-guided linear accelerator (MRI-LINAC) using adaptive radiotherapy. Here we review the current progress of radiation therapy during the last two decades.

Indexed as

BrachytherapyRadiotherapy, ConformalRadiotherapy, Intensity-ModulatedUterine Cervical NeoplasmsChemoradiotherapyFemaleHumansRadiotherapy Dosagecervical cancerradiology, interventionalradiotherapy, conformalradiotherapy, image-guidedradiotherapy, intensity-modulated

Identifiers

PMID37041022
PMCPMC10423558
OpenAlexW4364377845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.