Evidence map›Paper›PMID 37040812›Full record

ArticleActa biomaterialia2023

Optimization of peptide amphiphile-lipid raft interaction by changing peptide amphiphile lipophilicity.

Yan Zhou, Timmy Fyrner, Charlotte H Chen, Nicholas A Sather, Erin L Hsu, Samuel I Stupp, Malcolm L Snead

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta biomaterialia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yan ZhouCenter for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, 2250 Alcazar St, Los Angeles, CA 90033, USA. Electronic address: yzhou@usc.edu.
Timmy FyrnerSimpson Querrey Institute for BioNanotechnology, Northwestern University, Chicago, IL 60611, USA.
Charlotte H ChenSimpson Querrey Institute for BioNanotechnology, Northwestern University, Chicago, IL 60611, USA.
Nicholas A SatherSimpson Querrey Institute for BioNanotechnology, Northwestern University, Chicago, IL 60611, USA.
Erin L HsuSimpson Querrey Institute for BioNanotechnology, Northwestern University, Chicago, IL 60611, USA; Department of Orthopaedic Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Samuel I StuppSimpson Querrey Institute for BioNanotechnology, Northwestern University, Chicago, IL 60611, USA; Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA; Department of Chemistry, Northwestern University, Evanston, IL 60208, USA; Department of Medicine, Northwestern University, Chicago, IL 60611, USA; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.
Malcolm L SneadCenter for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, 2250 Alcazar St, Los Angeles, CA 90033, USA.
Northwestern University · USUniversity of Southern California · US

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LEONIDAS C. PLATANIAS · 1993 to 2026
$153.9M
Nanotechnology Strategies for Growth of Bones and TeethR01DE015920 · NIDCR · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SNEAD, MALCOLM L., STUPP, SAMUEL I · 2005 to 2015
$5.8M
Supramolecular nanofibers for recombinant growth factor-free spine fusionR01AR072721 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI STUPP, SAMUEL I · 2018 to 2022
$3.1M
STRUCTURAL BIOL RES: LUNG SURFACTANT PROTEINS, DISTRESSS10RR019071 · NCRR · NORTHWESTERN UNIVERSITY · PI RADHAKRISHNAN, ISHWAR · 2005 to 2005
$272k
600 MHz NMR Instrument Upgrade at Northwestern UniversityS10OD012016 · OD · NORTHWESTERN UNIVERSITY · PI RADHAKRISHNAN, ISHWAR · 2012 to 2012
$267k
NCI NIH HHS P30 CA060553NCRR NIH HHS S10 RR019071NIAMS NIH HHS R01 AR072721NIDCR NIH HHS R01 DE015920NIH HHS S10 OD012016
6 · The paper itself

Abstract

Various peptide amphiphile (PA) molecules have been developed to promote bone regeneration. Previously we discovered that a peptide amphiphile with a palmitic acid tail (C

Indexed as

Caveolin 1Membrane MicrodomainsAnimalsCholesterolHumansIntercellular Signaling Peptides and ProteinsMembrane LipidsMicePeptidesRNA, Small InterferingCaveolin 1CholesterolIntercellular Signaling Peptides and ProteinsMembrane LipidsPeptidesRNA, Small InterferingCaveolin-mediated endocytosisleucine-rich amelogenin peptide (LRAP)Lipid raftPeptide amphiphileSupramolecular nanofiberWnt signaling

Identifiers

PMID37040812
PMCPMC10225347
OpenAlexW4362735218

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.