Evidence map›Paper›PMID 37040713›Full record

ArticleCurrent biology : CB2023

Metabolism: How removal of damaged cells impacts energy availability in the retina.

Connor Lantz, Edward B Thorp

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Current biology : CB, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Connor LantzDepartment of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA; Feinberg Cardiovascular and Renal Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. Electronic address: connor.lantz@northwestern.edu.
Edward B ThorpDepartment of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA; Feinberg Cardiovascular and Renal Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA; Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA; The Heart Center, Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA. Electronic address: ebthorp@northwestern.edu.

Funding

Efferocytosis-Directed Inflammation Resolution and Repair in the Hypoxic HeartR01HL122309 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI THORP, EDWARD BENJAMIN · 2014 to 2024
$5.0M
Contributions of Myeloid Metabolism to Diastolic DysfunctionR01HL159964 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI THORP, EDWARD BENJAMIN · 2022 to 2024
$1.5M
NHLBI NIH HHS R01 HL122309NHLBI NIH HHS R01 HL159964
6 · The paper itself

Abstract

Once thought to be a quiescent process, elimination of damaged cells by professional phagocytes is now understood to modulate metabolite availability within tissues. A new study reveals that the retinal pigment epithelium serves as a local source of insulin after engulfment of damaged photoreceptors.

Indexed as

RetinaRetinal Pigment EpitheliumPhotoreceptor Cells

Identifiers

PMID37040713
PMCPMC10410992

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.