Evidence map›Paper›PMID 37040404›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Optimal generation of hepatic tissue-resident memory CD4 T cells requires IL-1 and IL-2.

Claire E Depew, Jordan A Rixon, Stephen J McSorley

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. PD-1 Inhibits CD4+ TRM-Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Claire E DepewDepartment of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California, Davis, CA 95616.ORCID 0000-0002-9341-9286
Jordan A RixonDepartment of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California, Davis, CA 95616.ORCID 0000-0002-8313-0702
Stephen J McSorleyDepartment of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California, Davis, CA 95616.ORCID 0000-0002-6363-3222
University of California, Davis · US

Funding

Animal Models of Infectious Diseases Training ProgramT32AI060555 · NIAID · UNIVERSITY OF CALIFORNIA DAVIS · PI MCSORLEY, STEPHEN J · 2004 to 2025
$3.3M
Spread and Release of Measles in the AirwaysR01AI132402 · NIAID · UNIVERSITY OF IOWA · PI SINN, PATRICK L · 2018 to 2022
$3.0M
Target antigen identification to improve Salmonella vaccinationR01AI139410 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI STEPHEN J MCSORLEY, Renee M Tsolis · 2018 to 2026
$2.9M
Salmonella-specific Th1 cell function and residenceR01AI139047 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MCSORLEY, STEPHEN J · 2019 to 2023
$1.9M
Acquisition of Covaris E220 and Sciclone G3 systems for high throughput sequencinS10OD010786 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI COMAI, LUCA · 2012 to 2012
$311k
NIAID NIH HHS R01 AI132402NIAID NIH HHS R01 AI139047NIAID NIH HHS R01 AI139410NIAID NIH HHS T32 AI060555NIH HHS S10 OD010786
6 · The paper itself

Abstract

Hepatic CD4 tissue-resident memory T cells (TRM) are required for robust protection against

Indexed as

CD4-Positive T-LymphocytesVaccinesAnimalsImmunologic MemoryInflammationInterleukin-1Interleukin-2LiverMemory T CellsMiceMice, Inbred C57BLInterleukin-1Interleukin-2VaccinesCD4 T cellsSalmonellatissue-resident memoryvaccination

Identifiers

PMID37040404
PMCPMC10120061
OpenAlexW4364353642

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.