Evidence map›Paper›PMID 37040392›Full record

ArticlePloS one2023

Effect of frequency and rhythmicity on flicker light-induced hallucinatory phenomena.

Ioanna Alicia Amaya, Nele Behrens, David John Schwartzman, Trevor Hewitt, Timo Torsten Schmidt

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Ioanna Alicia AmayaDepartment of Education and Psychology, Freie Universität Berlin, Berlin, Germany.ORCID 0000-0002-7815-6270
Nele BehrensDepartment of Education and Psychology, Freie Universität Berlin, Berlin, Germany.
David John SchwartzmanSackler Centre for Consciousness Science and Department of Informatics, University of Sussex, Brighton, United Kingdom.ORCID 0000-0002-3779-396X
Trevor HewittSackler Centre for Consciousness Science and Department of Informatics, University of Sussex, Brighton, United Kingdom.
Timo Torsten SchmidtDepartment of Education and Psychology, Freie Universität Berlin, Berlin, Germany.ORCID 0000-0003-1612-1301
University of Sussex · GBFreie Universität Berlin · DEHumboldt-Universität zu Berlin · DESigmund Freud Institut · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flicker light stimulation (FLS) uses stroboscopic light on closed eyes to induce transient visual hallucinatory phenomena, such as the perception of geometric patterns, motion, and colours. It remains an open question where the neural correlates of these hallucinatory experiences emerge along the visual pathway. To allow future testing of suggested underlying mechanisms (e.g., changes in functional connectivity, neural entrainment), we sought to systematically characterise the effects of frequency (3 Hz, 8 Hz, 10 Hz and 18 Hz) and rhythmicity (rhythmic and arrhythmic conditions) on flicker-induced subjective experiences. Using a novel questionnaire, we found that flicker frequency and rhythmicity significantly influenced the degree to which participants experienced simple visual hallucinations, particularly the perception of Klüver forms and dynamics (e.g., motion). Participants reported their experience of geometric patterns and dynamics was at highest intensity during 10 Hz rhythmic stimulation. Further, we found that frequency-matched arrhythmic FLS strongly reduced these subjective effects compared to equivalent rhythmic stimulation. Together, these results provide evidence that flicker rhythmicity critically contributes to the effects of FLS beyond the effects of frequency alone, indicating that neural entrainment may drive the induced phenomenal experience.

Indexed as

HallucinationsHumansPhotic Stimulation

Identifiers

PMID37040392
PMCPMC10089352
OpenAlexW4364353312

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.