Evidence map›Paper›PMID 37040295›Full record

ArticleResearch (Washington, D.C.)2023

Oxidized Dopamine Acrylamide Primer to Achieve Durable Resin-Dentin Bonding.

Leping Wu, Hui Shao, Yang Tao, Jingya Wu, Xinhui Wang, Qiufeng Nian, Shunli Zheng, Chris Ying Cao, Yuancong Zhao, Zheng Zhou and 2 more

Open access · goldAbstract read
In one paragraph

Article in Research (Washington, D.C.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Enhancing dentin bonding with catechol-based monomers by tailoring photoinitiator systems to overcome radical inhibition.Dental materials : official publication of the Academy of Dental Materials · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Bond preservation in caries-affected dentin restored with acrylamide-based adhesives.Dental materials : official publication of the Academy of Dental Materials · 2025
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Leping WuKey Laboratory of Oral Diseases Research of Anhui Province, College and Hospital of Stomatology, Anhui Medical University, 81 Meishan Road, Hefei 230032, China.
Hui ShaoKey Laboratory of Oral Diseases Research of Anhui Province, College and Hospital of Stomatology, Anhui Medical University, 81 Meishan Road, Hefei 230032, China.
Yang TaoKey Laboratory of Oral Diseases Research of Anhui Province, College and Hospital of Stomatology, Anhui Medical University, 81 Meishan Road, Hefei 230032, China.
Jingya WuKey Laboratory of Oral Diseases Research of Anhui Province, College and Hospital of Stomatology, Anhui Medical University, 81 Meishan Road, Hefei 230032, China.
Xinhui WangKey Laboratory of Oral Diseases Research of Anhui Province, College and Hospital of Stomatology, Anhui Medical University, 81 Meishan Road, Hefei 230032, China.
Qiufeng NianKey Laboratory of Oral Diseases Research of Anhui Province, College and Hospital of Stomatology, Anhui Medical University, 81 Meishan Road, Hefei 230032, China.
Shunli ZhengKey Laboratory of Oral Diseases Research of Anhui Province, College and Hospital of Stomatology, Anhui Medical University, 81 Meishan Road, Hefei 230032, China.
Chris Ying CaoKey Laboratory of Oral Diseases Research of Anhui Province, College and Hospital of Stomatology, Anhui Medical University, 81 Meishan Road, Hefei 230032, China.
Yuancong ZhaoKey Laboratory of Advanced Technology for Materials of Education Ministry, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China.
Zheng ZhouSchool of Dentistry, University of Detroit Mercy, Detroit, MI 48208-2576, USA.
Hai Ming WongFaculty of Dentistry, The University of Hong Kong, 34 Hospital Road, The Prince Philip Dental Hospital, Hong Kong 999077, China.
Quan-Li LiKey Laboratory of Oral Diseases Research of Anhui Province, College and Hospital of Stomatology, Anhui Medical University, 81 Meishan Road, Hefei 230032, China.
Nanjing Jiangning Hospital · CNUniversity of Detroit Mercy · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The durability of the resin-dentin bonding interface is a key issue in clinical esthetic dentistry. Inspired by the extraordinary bioadhesive properties of marine mussels in a wet environment, we designed and synthetized N-2-(3,4-dihydroxylphenyl) acrylamide (DAA) according to the functional domain of mussel adhesive proteins. DAA's properties of collagen cross-linking, collagenase inhibition, inducing collagen mineralization in vitro, and as a novel prime monomer for clinical dentin adhesion use, its optimal parameters, and effect on the adhesive longevity and the bonding interface's integrity and mineralization, were evaluated in vitro and in vivo. The results showed that oxide DAA can inhibit the activity of collagenase and cross collagen fibers to improve the anti-enzymatic hydrolysis of collagen fibers and induce intrafibrillar and interfibrillar collagen mineralization. As a primer used in the etch-rinse tooth adhesive system, oxide DAA can improve the durability and integrity of the bonding interface by anti-degradation and mineralization of the exposed collagen matrix. Oxidized DAA (OX-DAA) is a promising primer for improving dentin durability; using 5% OX-DAA ethanol solution and treating the etched dentin surface for 30 s is the optimal choice when used as a primer in the etch-rinse tooth adhesive system.

Identifiers

PMID37040295
PMCPMC10079285
OpenAlexW4327742995

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.