Evidence map›Paper›PMID 37039453›Full record

ArticleeLife2023

A genetic variant of fatty acid amide hydrolase (FAAH) exacerbates hormone-mediated orexigenic feeding in mice.

Georgia Balsevich, Gavin N Petrie, Daniel E Heinz, Arashdeep Singh, Robert J Aukema, Avery C Hunker, Haley A Vecchiarelli, Hiulan Yau, Martin Sticht, Roger J Thompson and 5 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Genetic Tools in Rodents to Study Cannabinoid Functions.Current topics in behavioral neurosciences · 2026
    Review
  4. Review
  5. Article
  6. Ghrelin Recruits the Endocannabinoid System to Modulate Food Reward.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

Georgia BalsevichHotchkiss Brain Institute, University of Calgary, Calgary, Canada.ORCID 0000-0002-7839-018X
Gavin N PetrieHotchkiss Brain Institute, University of Calgary, Calgary, Canada.
Daniel E HeinzNeurohomeostasis Research Group, Department of Psychiatry and Psychotherapy, University Hospital Bonn, Bonn, Germany.ORCID 0000-0001-7103-9621
Arashdeep SinghMonell Chemical Senses Center and Department of Neuroscience, University of Pennsylvania, Philadelphia, United States.ORCID 0000-0002-2477-1438
Robert J AukemaHotchkiss Brain Institute, University of Calgary, Calgary, Canada.ORCID 0000-0003-3490-3390
Avery C HunkerDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, United States.
Haley A VecchiarelliHotchkiss Brain Institute, University of Calgary, Calgary, Canada.ORCID 0000-0001-6331-6107
Hiulan YauHotchkiss Brain Institute, University of Calgary, Calgary, Canada.
Martin StichtHotchkiss Brain Institute, University of Calgary, Calgary, Canada.
Roger J ThompsonHotchkiss Brain Institute, University of Calgary, Calgary, Canada.ORCID 0000-0002-7019-7246
Francis S LeeWeill Cornell Medical College, Cornell University, New York, United States.ORCID 0000-0002-7108-9650
Larry S ZweifelDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, United States.ORCID 0000-0003-3465-5331
Prasanth K ChelikaniTexas Tech University, School of Veterinary Medicine, Amarillo, United States.
Nils C GassenNeurohomeostasis Research Group, Department of Psychiatry and Psychotherapy, University Hospital Bonn, Bonn, Germany.
Matthew N HillHotchkiss Brain Institute, University of Calgary, Calgary, Canada.ORCID 0000-0001-7144-9209
Allen Institute for Brain Science · USUniversity Hospital Bonn · DEUniversity of Washington · USCornell University · USMonell Chemical Senses Center · USTexas Tech University · US

Funding

University of Washington Center of Excellence in Opioid Addiction ResearchP30DA048736 · NIDA · UNIVERSITY OF WASHINGTON · PI Charles Chavkin · 2019 to 2026
$13.0M
NIDA NIH HHS P30 DA048736
6 · The paper itself

Abstract

Fatty acid amide hydrolase (FAAH) degrades the endocannabinoid anandamide. A polymorphism in

Indexed as

AMP-Activated Protein KinasesEndocannabinoidsAgouti-Related ProteinAmidohydrolasesAnimalsArachidonic AcidsFatty Acid Amide HydrolasesHumansMiceObesityPolyunsaturated AlkamidesAgouti-Related ProteinAmidohydrolasesAMP-Activated Protein KinasesanandamideArachidonic AcidsEndocannabinoidsFatty Acid Amide HydrolasesPolyunsaturated AlkamidesendocannabinoidsFAAHfeedingglucocorticoidsmouseneuroscienceobesity

Identifiers

PMID37039453
PMCPMC10159625
OpenAlexW4364351814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.