ArticleJournal of the American Chemical Society2023
Compact Rotaxane Superbases.
Article in Journal of the American Chemical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Inverted metal-free active template synthesis of rotaxanes via axle‑mediated macrocyclization.Nature chemistry · 2026Article
- Successive Ring Expansion Strategies for the Synthesis of Macrocycles and Medium-Sized Rings.Chemical reviews · 2026Article
- Precision Switching and Coupled Motion in a [3]Rotaxane Molecular Machine.Angewandte Chemie (International ed. in English) · 2026Article
- Metal-Free Active Template: A Straightforward Route to 4-Aminopyridinium-Based Rotaxane Molecular Shuttles.Angewandte Chemie (International ed. in English) · 2026Article
- Spatial Assembly of Mechanically Planar Chiral Rotaxanes on Rationally Designed Cavitands.Angewandte Chemie (International ed. in English) · 2025Article
- Rotaxane synthesisRSC advances · 2025Article
- A Dive Into Forty Years of Research on Organic Superbases: From Design to Applications.Journal of computational chemistry · 2025Review
- Programmable molecular dethreading towards tunable drug release.Nature communications · 2025Article
- Crown Ether-Peptide Rotaxanes.Angewandte Chemie (International ed. in English) · 2025Article
- A Thiourea-Based Rotaxane Catalyst: Nucleophilic Fluorination Phase-Transfer Process Unlocked by the Mechanical Bond.Organic letters · 2025Article
- Skeletal Editing of Mechanically Interlocked Molecules: Nitrogen Atom Deletion from Crown Ether-Dibenzylammonium Rotaxanes.Journal of the American Chemical Society · 2024Article
- Urea-Based [2]Rotaxanes as Effective Phase-Transfer Organocatalysts: Hydrogen-Bonding Cooperative Activation Enabled by the Mechanical Bond.Journal of the American Chemical Society · 2024Article
- Strong Bases Design: Key Techniques and Stability Issues.International journal of molecular sciences · 2024Article
- Molecular entanglement can strongly increase basicity.Communications chemistry · 2024Review
- A Modular Strategy for the Synthesis of Macrocycles and Medium-Sized Rings via Cyclization/Ring Expansion Cascade Reactions.Journal of the American Chemical Society · 2024Article
- Series of Protonated Nitrogen Bases with a Weakly Coordinating Counteranion: Observation of theACS organic & inorganic Au · 2024Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Challenges for the development of efficacious new superbases include their ease of synthesis, chemical stability, and high basicity, while minimizing nucleophilicity is important for reducing unwanted side reactions. Here, we introduce a new family of organic superbases, compact amine-crown ether rotaxanes, which show desirable characteristics in all these respects. Metal-free active template synthesis provides access to a range of rotaxanes with as little as three atoms between the stoppering groups, locking the location of a small crown ether (21C7 and 24C8 derivatives) over the amine group of the axle. The forced proximity of the interlocked protophilic components results in p
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.