ReviewThe Journal of international medical research2023
Utility of neutrophil-to-high-density lipoprotein-cholesterol ratio in patients with coronary artery disease: a narrative review.
Review in The Journal of international medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 30 citations in OpenAlex.
- Neutrophil-to-HDL-C Ratio and Anatomically Significant Multivessel Disease Across Acute Coronary Syndrome Phenotypes.Medeniyet medical journal · 2026Article
- Association Between Neutrophil-to-High-Density Lipoprotein-Cholesterol Ratio and Coronary Artery Calcium: A Cross-Sectional Study.Biomedicines · 2026Article
- The relationship of neutrophil to high-density lipoprotein cholesterol ratio with all-cause mortality in patients undergoing cardiac surgery: a retrospective cohort study.Journal of cardiothoracic surgery · 2026Article
- Clinical significance and prognostic value of high-density lipoprotein cholesterol-based markers in very young patients with coronary artery disease: a retrospective study.Lipids in health and disease · 2026Article
- White blood cells and neutrophil-to-high density lipoprotein ratio as predictive markers of left ventricular dysfunction in heart failure.World journal of methodology · 2026Article
- Association of the Neutrophil to High-Density Lipoprotein Cholesterol Ratio and Platelet to High-Density Lipoprotein Cholesterol Ratio with Early Vascular Aging.Journal of inflammation research · 2026Article
- The neutrophil to high-density lipoprotein cholesterol ratio is associated with disease severity in hypertriglyceridemic acute pancreatitis.BMC gastroenterology · 2025Article
- Admission neutrophil-to-high-density lipoprotein cholesterol ratio and the risk of preoperative early rebleed in aneurysmal subarachnoid hemorrhage.European journal of medical research · 2025Article
- Observational
- Association between neutrophil/ high-density lipoprotein cholesterol ratio and BMI in three Argentinean Indigenous communities.Biochemistry and biophysics reports · 2025Article
- Progress in Prognostic Metabolic Biomarkers for Coronary Artery Disease Patients Post-Percutaneous Coronary Intervention.Reviews in cardiovascular medicine · 2025Review
- Association of High-Density Lipoprotein Cholesterol-Based Inflammatory Markers With MASLD and Significant Liver Fibrosis in US Adults: Insights From NHANES 2017-2020.Clinical and translational gastroenterology · 2025Article
- Development of a 5-Year Risk Prediction Model for Transition From Prediabetes to Diabetes Using Machine Learning: Retrospective Cohort Study.Journal of medical Internet research · 2025Article
- Sex differences of neutrophil to high-density lipoprotein cholesterol ratio in predicting the severity of coronary lesions in acute coronary syndrome patients.Lipids in health and disease · 2025Article
- Elevated neutrophil to high-density lipoprotein ratio predicts pneumonia in patients with intracerebral hemorrhage.Frontiers in medicine · 2025Article
- Novel Inflammatory Markers and Their Association with the Severity of Hypertriglyceridemia-Associated Acute Pancreatitis.Journal of inflammation research · 2025Article
- Age-dependent prognostic significance of neutrophil-to-HDL ratio in hepatocellular carcinoma patients.Frontiers in oncology · 2025Article
- Prognostic Value of Neutrophil, Monocyte, Lymphocyte, and Platelet/High-Density Lipoprotein Ratios in Ischemic Heart Disease: An NHANES Analysis.Medicina (Kaunas, Lithuania) · 2024Article
- Neutrophil-to-High-Density Lipoprotein Ratio (NHR) and Neutrophil-to-Lymphocyte Ratio (NLR) as prognostic biomarkers for incident cardiovascular disease and all-cause mortality: A comparison study.American journal of preventive cardiology · 2024Article
- Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The neutrophil-to-high-density lipoprotein-cholesterol ratio (NHR) is thought to reflect inflammatory status and dyslipidaemia, both of which play significant roles in coronary artery disease (CAD). The objective of this narrative review is to summarise the results of studies that have explored the utility of NHR for the diagnosis and management of CAD. The PubMed, Google Scholar, Scopus, Embase and Web of Science databases were searched for articles related to NHR from their inception to October 2022. Seven relevant articles were obtained for review. There were unclear relationships of NHR with age, sex, smoking status, hypertension and diabetes. However, NHR had a sensitivity and specificity as high as 94.8% and 59%, respectively, for the identification of significant coronary stenosis. NHR was also a superior predictor of prognosis to conventional parameters. NHR had a sensitivity and specificity as high as 77.6% and 74.2%, respectively, for the prediction of adverse events, including mortality, associated with acute coronary syndrome. Thus, NHR could be used in clinical cardiovascular medicine for risk stratification and the prediction of the short-term and long-term outcomes of CAD. However, more studies are required before a quantitative assessment of the efficacy of NHR for use in patient management can be completed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.