Evidence map›Paper›PMID 37038890›Full record

ReviewHippocampus2023

Computational cross-species views of the hippocampal formation.

Seren L Zhu, Kaushik J Lakshminarasimhan, Dora E Angelaki

Open access · greenAbstract readReview
In one paragraph

Review in Hippocampus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Seren L ZhuCenter for Neural Science, New York University, New York, New York, USA.
Kaushik J LakshminarasimhanCenter for Theoretical Neuroscience, Zuckerman Mind Brain Behavior Institute, Columbia University, New York, New York, USA.ORCID 0000-0003-3932-2616
Dora E AngelakiCenter for Neural Science, New York University, New York, New York, USA.
New York University · USAllen Institute for Brain Science · US

Funding

Project C: Neural basis of causal inference in continuous navigationU19NS118246 · NINDS · UNIVERSITY OF ROCHESTER · PI DEANGELIS, GREGORY C · 2020 to 2024
$12.0M
NEURAL MECHANISMS OF VESTIBULAR FUNCTIONR01DC004260 · NIDCD · WASHINGTON UNIVERSITY · PI ANGELAKI, DORA · 1999 to 2025
$11.6M
CRCNS: Neural computations for continuous control in virtual reality foragingR01NS120407 · NINDS · CARNEGIE-MELLON UNIVERSITY · PI PITKOW, ZACHARY SAMUEL · 2020 to 2024
$2.0M
NIDCD NIH HHS R01 DC004260NINDS NIH HHS R01 NS120407NINDS NIH HHS U19 NS118246
6 · The paper itself

Abstract

The discovery of place cells and head direction cells in the hippocampal formation of freely foraging rodents has led to an emphasis of its role in encoding allocentric spatial relationships. In contrast, studies in head-fixed primates have additionally found representations of spatial views. We review recent experiments in freely moving monkeys that expand upon these findings and show that postural variables such as eye/head movements strongly influence neural activity in the hippocampal formation, suggesting that the function of the hippocampus depends on where the animal looks. We interpret these results in the light of recent studies in humans performing challenging navigation tasks which suggest that depending on the context, eye/head movements serve one of two roles-gathering information about the structure of the environment (active sensing) or externalizing the contents of internal beliefs/deliberation (embodied cognition). These findings prompt future experimental investigations into the information carried by signals flowing between the hippocampal formation and the brain regions controlling postural variables, and constitute a basis for updating computational theories of the hippocampal system to accommodate the influence of eye/head movements.

Indexed as

HippocampusSpace PerceptionAnimalsBrainCognitionHumansPrimatesactive sensingembodied cognitioneye movementshippocampusprimate

Identifiers

PMID37038890
PMCPMC10947336
OpenAlexW4364353616

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.