Evidence map›Paper›PMID 37038620›Full record

ArticleJournal of cellular and molecular medicine2023

The effects of patchouli alcohol and combination with cisplatin on proliferation, apoptosis and migration in B16F10 melanoma cells.

Kai-Fu Chang, Hung-Chih Lai, Shan-Chih Lee, Xiao-Fan Huang, Ya-Chih Huang, Tien-Erh Chou, Chih-Yen Hsiao, Nu-Man Tsai

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  9. Epigenomics · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Kai-Fu ChangDepartment of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan, R.O.C.ORCID 0000-0003-1640-1960
Hung-Chih LaiDivision of Hematology and Oncology, Department of Internal Medicine, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan, R.O.C.
Shan-Chih LeeDepartment of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung, Taiwan, R.O.C.ORCID 0000-0001-6583-1575
Xiao-Fan HuangDepartment of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan, R.O.C.ORCID 0000-0001-5164-5966
Ya-Chih HuangDepartment of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan, R.O.C.
Tien-Erh ChouDepartment of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan, R.O.C.
Chih-Yen HsiaoDivision of Nephrology, Department of Internal Medicine, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chia-Yi, Taiwan, R.O.C.ORCID 0000-0003-1199-6977
Nu-Man TsaiDepartment of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan, R.O.C.ORCID 0000-0002-2629-1833
Chung Shan Medical University Hospital · TWChia-Yi Christian Hospital · TWNational Taiwan University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanoma is a highly metastatic cancer with a low incidence rate, but a high mortality rate. Patchouli alcohol (PA), a tricyclic sesquiterpene, is considered the main active component in Pogostemon cablin Benth, which improves wound healing and has anti-tumorigenic activity. However, the pharmacological action of PA on anti-melanoma remains unclear. Thus, the present study aimed to investigate the role of PA in the proliferation, cell cycle, apoptosis and migration of melanoma cells. These results indicated that PA selectively inhibited the proliferation of B16F10 cells in a dose- and time-dependent manner. It induced cell cycle arrest at the G

Indexed as

MelanomaSesquiterpenesApoptosisCell Line, TumorCell ProliferationCisplatinHumansCisplatinpatchouli alcoholSesquiterpenescell apoptosisdrug combinationmelanomamigrationpatchouli alcohol

Identifiers

PMID37038620
PMCPMC10183711
OpenAlexW4363651627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.