ArticleInfection and drug resistance2023
6084 Cases of Adult Tetanus from China: A Literature Analysis.
Article in Infection and drug resistance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 10 citations in OpenAlex.
- A phase III clinical trial on the immunogenicity of a tetanus vaccine, adsorbed in individuals aged 18 years and above in China.Frontiers in immunology · 2026Trial
- Chinese expert consensus on tetanus prophylaxis in major trauma (2026 Edition).Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2026Article
- Clinical characteristics, management, and outcomes of severe tetanus in the intensive care unit.BMC infectious diseases · 2026Observational
- Population waning trajectories of vaccine-induced tetanus immunity in Zhejiang, China.Frontiers in immunology · 2026Article
- Management and outcome of adult generalized tetanus patients in a tertiary hospital in Anhui, China: a retrospective study.Frontiers in public health · 2026Article
- Tetanus: recognition and management.The Lancet. Infectious diseases · 2025Review
- Current Status and Factors of Vaccine Hesitancy in Tetanus Vaccination Among Traumatic Patients - China, 2024.China CDC weekly · 2025Article
- Surgical treatment of mammalian bites----experience in the management of facial wounds by dog and cat bite in China.International journal of burns and trauma · 2024Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To describe the clinical characteristics, treatments, and outcomes of tetanus and determine the most appropriate focus for tetanus prevention and treatment to reduce morbidity and mortality in China. Methods: Four databases, including the Chinese Bio-Medical Literature Database, Chinese National Knowledge Infrastructure, Chinese Scientific Journal Database, and Wan-fang Data, were searched from 1 January, 2000 to 30 October, 2022. Results: In total, 151 articles including 6084 tetanus patients met the inclusion criteria. Additionally, 5925 patients had their gender recorded in detail, among which 66.67% (3950/5925) were male, and 33.33% (1975/ 5925) were female. The average age in the detailed records was reported in 4773 cases, with an overall average age of 46.69. The number of patients' places of residence was 580. Those from rural areas comprised the highest percentage with 88.62% (514 / 580). The causes of injury were recorded in 1592 cases in total; injuries caused by metals, wood, and wooden spikes accounted for the highest percentage with 54.52% (868/1592). Patient outcomes were recorded in 4305 cases, with a mortality of 9.34% (402/4305). The leading causes of death included treatment terminated by family members, asphyxia due to persistent spasms, respiratory failure, and autonomic dysfunction, family automatic abandonment and asphyxia accounted for the highest percentage, both 24.00% (54/225). Conclusion: The overall success rate of tetanus treatment in China has dramatically improved, but the prevention and control of non-neonatal tetanus is still challenging. Focus should be placed on the prevention of adult tetanus and standardizing the use of sedative and spasmolytic drugs. Additionally, medical professionals should popularize tetanus prevention and treatment knowledge among the people and strengthen training in grass-roots hospitals.
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