Evidence map›Paper›PMID 37038393›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2022

Dual-source photon-counting CT: consistency in spectral results at different acquisition modes and heart rates.

Leening P Liu, Nadav Shapira, Pooyan Sahbaee, Harold I Litt, Marcus Y Chen, Peter B Noël

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Leening P LiuDepartment of Bioengineering and Department of Radiology, Perelman School of Medicine, Philadelphia, PA, USA.
Nadav ShapiraNoël are with the Department of Radiology, Perelman School of Medicine, Philadelphia, PA, USA.
Pooyan SahbaeeSiemens Medical Solutions, Malvern, PA, USA.
Harold I LittNoël are with the Department of Radiology, Perelman School of Medicine, Philadelphia, PA, USA.
Marcus Y ChenNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Peter B NoëlNoël are with the Department of Radiology, Perelman School of Medicine, Philadelphia, PA, USA.

Funding

Patient-specific, high-sensitivity spectral CT for assessment of pancreatic cancerR01EB030494 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI GANG, JIANAN GRACE, NOËL, PETER B · 2021 to 2024
$2.4M
NIBIB NIH HHS R01 EB030494
6 · The paper itself

Abstract

Cardiac CT is a useful tool for cardiovascular diagnostics that offers different acquisition modes, each with its advantages. The development of direct converting detector technology has resulted in the clinical translation of dual-source photon-counting CT. This takes advantage of the improved image quality at high heart rates from dual-source CT while making available spectral results for more precise material characterization and quantification. To evaluate the stability of spectral results among different acquisition modes and heart rates, a cardiac motion phantom with a rod mimicking a 50% coronary stenosis was scanned with a dual-source photon-counting CT in three different acquisition modes (retrospective dual-source spiral, prospective dual-source step-and-shoot, dual-source flash spiral) and at different heart rates (60, 80, 100 bpm). Dice scores of stenosed regions relative to a static scan, eccentricity of non-stenosed regions, full width half max, and normalized area under the curve of line profiles were calculated for iodine density maps, and virtual mono-energetic images at 40 and 70 keV. Dice scores and eccentricity were consistent and not significantly affected by acquisition mode or heart rate for spectral results. Full width half max and normalized area under the curve similarly illustrated minor differences between acquisition modes and heart rates. The consistency in these metrics demonstrate preserved image structure and allows for the use of spectral results with high confidence. Dual-source photon-counting CT will enable cardiovascular diagnostics with better material characterization and differentiation.

Indexed as

Cardiac CTPhoton-counting CTSpectral CT

Identifiers

PMID37038393
PMCPMC10082999

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.