ReviewCritical care (London, England)2023
The intracranial compartmental syndrome: a proposed model for acute brain injury monitoring and management.
Review in Critical care (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Comparative Effectiveness Study on Catheter Locking Device Versus Standard Ventriculostomy for Surgical Management of Traumatic Brain Injury Patients With Intracranial Compartment Syndrome
A Comparative-effectiveness Study on Expansion Craniotomy Versus Decompressive Craniectomy for Surgical Management of Traumatic Brain Injury in Patients With Intracranial Compartment Syndrome
Who cites it
33 citing papers in PubMed, 46 citations in OpenAlex.
- The Neurological and Hemodynamics Safety of an Airway Clearance Technique in Patients with Acute Brain Injury: An Analysis of Intracranial Pressure Pulse Morphology Using a Non-Invasive Sensor.Sensors (Basel, Switzerland) · 2024Trial
- Intracranial pressure physiology, monitoring and individualized management in the acute brain injured patient.Intensive care medicine · 2026Review
- Intracranial Pressure Estimation Using B4C Device: A Systematic Review on the Validation Studies.Neurocritical care · 2026Review
- Impaired Intracranial Compliance: A New Hypertension-Mediated Brain Organ Damage?High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026Article
- Bridging the gap: pragmatic neuromonitoring and management of traumatic brain injury in resource-limited settings.Intensive care medicine · 2026Article
- CT Quantification of Intraventricular Hemorrhage Volume in Poor-Grade Aneurysmal Subarachnoid Hemorrhage: Impact on Mortality and Long-Term Disability.Neurocritical care · 2026Article
- Invasive Cerebral Oximetry: What Can Go Wrong? Seven Pitfalls you should know.Neurocritical care · 2026Article
- Surgical Management of Traumatic Brain Injury Based on Intracranial Compliance: Toward Personalized Decision-Making.Brain sciences · 2026Review
- Neuroworsening in traumatic brain injury: A consensus of the Latin American Brain Injury Consortium (LABIC) and the Latin American Federation of Neurosurgical Societies (FLANC) expert group.Neurosurgical review · 2026Article
- Cerebral perfusion pressure trajectories and cumulative exposure metrics predict in-hospital mortality in acute brain injury.Frontiers in medicine · 2026Article
- Fluid therapy in traumatic brain injury with the resuscitation, optimization, stabilization, and evacuation (ROSE) concept approach.Critical care science · 2026Article
- Decision-Making in Neurotrauma: a multidimensional model of cognitive and contextual factors influencing surgical judgment in the acute care setting.Brain & spine · 2026Review
- Article
- Four Distinct Dynamic Intracranial Pressure Trajectories and Their Prognostic Implications in Acute Brain Injury: A Multicenter Cohort Study.CNS neuroscience & therapeutics · 2026Article
- The clinical significance of intracranial pressure waveform analysis in brain-injured patients.Critical care science · 2026Review
- Is There a Place for Cerebrospinal Fluid External Lumbar Drainage in Posttraumatic Intracranial Hypertension? Pros, Cons, and Uncertainties.Neurocritical care · 2025Article
- Monro-Kellie 4.0: moving from intracranial pressure to intracranial dynamics.Critical care (London, England) · 2025Review
- Machine learning approach for noninvasive intracranial pressure estimation using pulsatile cranial expansion waveforms.NPJ digital medicine · 2025Article
- Evaluation of monitoring critical ill children with traumatic brain injury.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2025Article
- Characterization of intracranial compliance in healthy subjects using a noninvasive method - results from a multicenter prospective observational study.Journal of clinical monitoring and computing · 2024Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For decades, one of the main targets in the management of severe acute brain injury (ABI) has been intracranial hypertension (IH) control. However, the determination of IH has suffered variations in its thresholds over time without clear evidence for it. Meanwhile, progress in the understanding of intracranial content (brain, blood and cerebrospinal fluid) dynamics and recent development in monitoring techniques suggest that targeting intracranial compliance (ICC) could be a more reliable approach rather than guiding actions by predetermined intracranial pressure values. It is known that ICC impairment forecasts IH, as intracranial volume may rapidly increase inside the skull, a closed bony box with derisory expansibility. Therefore, an intracranial compartmental syndrome (ICCS) can occur with deleterious brain effects, precipitating a reduction in brain perfusion, thereby inducing brain ischemia. The present perspective review aims to discuss the ICCS concept and suggest an integrative model for the combination of modern invasive and noninvasive techniques for IH and ICC assessment. The theory and logic suggest that the combination of multiple ancillary methods may enhance ICC impairment prediction, pointing proactive actions and improving patient outcomes.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.