Trial reportJournal of cardiothoracic surgery2023
The effectiveness of early surgical stabilization for multiple rib fractures: a multicenter randomized controlled trial.
Trial report in Journal of cardiothoracic surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Guideline
- Clinical outcome analysis for surgical fixation versus conservative treatment on rib fractures: a systematic evaluation and meta-analysis.World journal of emergency surgery : WJES · 2025Pooled it
- Early surgical stabilization of rib fractures in patients with mechanical ventilation-dependent respiratory failure secondary to severe chest wall injury: a retrospective cohort study.Journal of thoracic disease · 2026Article
- Rapid sequence versus early surgical stabilization of severe chest wall injuries: a propensity score-matched analysis from a multicenter trauma registry.Critical care (London, England) · 2026Article
- A study on the optimal timing for Rib fracture surgery: A report from a single center is earlier surgery always better?Journal of orthopaedic surgery and research · 2026Article
- Surgical Stabilization of Rib Fractures in Geriatric Trauma Patients: A National Trauma Data Bank Review.Journal of the American Geriatrics Society · 2026Article
- Clinical value of surgical intervention and decision-making dilemmas for elderly patients of rib fractures: a systematic review and meta-analysis.Journal of thoracic disease · 2026Article
- Hemodynamics of active abdominal compression decompression CPR in a rat model of multiple rib fractures with asphyxial cardiac arrest.Scientific reports · 2025Article
- Chest Wall Injury Society guidelines for surgical stabilization of rib fractures: Indications, contraindications, and timing.The journal of trauma and acute care surgery · 2025Article
- Influence of Diabetes Mellitus on Perioperative Outcomes Following Surgical Stabilization of Rib Fractures: A National Health Insurance Research Database Analysis.Medicina (Kaunas, Lithuania) · 2025Article
- Surgical stabilization of rib fractures improves survival in functionally dependent trauma patients.World journal of emergency surgery : WJES · 2025Article
- Resorbable 3D-Printed Osteosynthetic Plates for Rib Fracture Repair.Advanced healthcare materials · 2025Article
- Impact of Surgical Stabilization of Flail Chest Injuries on Postoperative Computed Tomography Lung Volumes.Journal of clinical medicine · 2025Article
- Factors influencing Vizient length of stay index after surgical stabilization of rib fractures (SSRF).Trauma surgery & acute care open · 2025Article
- To fix or let them flail: the who, what and when of rib fixation.Trauma surgery & acute care open · 2025Review
- Short-term follow-up of single-port thoracoscopic rib fracture reduction and internal fixation for the treatment of multiple rib fractures.Archives of orthopaedic and trauma surgery · 2024Article
- Short-term follow-up of single-port thoracoscopic rib fracture reduction and internal fixation for the treatment of multiple rib fractures.Archives of orthopaedic and trauma surgery · 2024Article
- Comminuted Paraspinal Rib Fractures with Resultant Impending Penetrating Aortic Injury Requiring Costovertebral Rib Fixation: A Case Report.Medicina (Kaunas, Lithuania) · 2024Article
- Erector spinae plane block (ESPB) enhances hemodynamic stability decreasing analgesic requirements in surgical stabilization of rib fractures (SSRFs).World journal of emergency surgery : WJES · 2024Article
- Surgical stabilization of rib fractures (SSRF): the WSES and CWIS position paper.World journal of emergency surgery : WJES · 2024Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMultiple rib fractures (≥ 3 displaced rib fractures and/or flail chest) are severe chest trauma with high morbidity and mortality. Rib fixation has become the first choice for multiple rib fracture treatment. However, the timing of surgical rib fixation is unclear. MATERIALS AND
methodsThe present study explored whether early rib fracture fixation can improve the outcome of multiple rib fractures. The present research included patients who were hospitalized in three Jiangsu hospitals following diagnosis with multiple rib fractures. Patients received early rib fracture fixation (≤ 48 h) or delayed rib fracture fixation (> 48 h) utilizing computer-based random sequencing (in a 1:1 ratio). The primary outcome measures included hospital length of stay, intensive care unit (ICU) stay, mechanical ventilation, inflammatory cytokine levels, infection marker levels, infection, and mortality.
resultsA total of 403 individuals were classified into two groups, namely, the early group (n = 201) and the delayed group (n = 202). Patients belonging to the two groups had similar baseline clinical data, and there were no statistically significant differences between them. Early rib fracture fixation greatly decreased the length of stay in the ICU (4.63 days vs. 6.72 days, p < 0.001), overall hospital stay (10.15 days vs. 12.43 days, p < 0.001), ventilation days (3.67 days vs. 4.55 days, p < 0.001), and hospitalization cost (6900 USD vs. 7600 USD, p = 0.008). Early rib fracture fixation can decrease inflammatory cytokine levels and infection marker levels, prevent hyperinflammation and improve infection in patients with multiple rib fractures. The timing of rib fracture fixation does not influence the surgical procedure time, operative blood loss, 30-day all-cause mortality, or surgical site infection.
conclusionThe findings from the present research indicated that early rib fracture fixation (≤ 48 h) is a safe, rational, effective and economical strategy and worth clinical promotion.
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