Evidence map›Paper›PMID 37037970›Full record

ArticleAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2023

An integrated strategy of spectrum-effect relationship and near-infrared spectroscopy rapid evaluation based on back propagation neural network for quality control of Paeoniae Radix Alba.

Qi Wang, Huaqiang Li, Jinling You, Binjun Yan, Weifeng Jin, Menglan Shen, Yunjie Sheng, Bingqian He, Xinrui Wang, Xiongyu Meng and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Nanomaterial-based sensors in analytical chemistry.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Qi Wang *School of Pharmaceutical Sciences, Traditional Chinese Medicine Resources and Quality Evaluation Ressearch, Zhejiang Chinese Medical University, Sphingolipid Metabolomics, Hangzhou, 310053, China.
Huaqiang Li *School of Pharmaceutical Sciences, Traditional Chinese Medicine Resources and Quality Evaluation Ressearch, Zhejiang Chinese Medical University, Sphingolipid Metabolomics, Hangzhou, 310053, China.
Jinling YouSchool of Pharmaceutical Sciences, Traditional Chinese Medicine Resources and Quality Evaluation Ressearch, Zhejiang Chinese Medical University, Sphingolipid Metabolomics, Hangzhou, 310053, China.
Binjun YanSchool of Pharmaceutical Sciences, Traditional Chinese Medicine Resources and Quality Evaluation Ressearch, Zhejiang Chinese Medical University, Sphingolipid Metabolomics, Hangzhou, 310053, China.
Weifeng JinSchool of Pharmaceutical Sciences, Traditional Chinese Medicine Resources and Quality Evaluation Ressearch, Zhejiang Chinese Medical University, Sphingolipid Metabolomics, Hangzhou, 310053, China.
Menglan ShenSchool of Pharmaceutical Sciences, Traditional Chinese Medicine Resources and Quality Evaluation Ressearch, Zhejiang Chinese Medical University, Sphingolipid Metabolomics, Hangzhou, 310053, China.
Yunjie ShengSchool of Pharmaceutical Sciences, Traditional Chinese Medicine Resources and Quality Evaluation Ressearch, Zhejiang Chinese Medical University, Sphingolipid Metabolomics, Hangzhou, 310053, China.
Bingqian HeAcademy of Chinese Medical Science, School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, 548 Binwen Road, Binjiang District310053, Hangzhou, Zhejiang Province, People's Republic of China.
Xinrui WangSchool of Pharmaceutical Sciences, Traditional Chinese Medicine Resources and Quality Evaluation Ressearch, Zhejiang Chinese Medical University, Sphingolipid Metabolomics, Hangzhou, 310053, China.
Xiongyu MengSchool of Pharmaceutical Sciences, Traditional Chinese Medicine Resources and Quality Evaluation Ressearch, Zhejiang Chinese Medical University, Sphingolipid Metabolomics, Hangzhou, 310053, China. mengxiongyu@zcmu.edu.cn.ORCID http://orcid.org/0000-0003-0794-1308
Luping QinSchool of Pharmaceutical Sciences, Traditional Chinese Medicine Resources and Quality Evaluation Ressearch, Zhejiang Chinese Medical University, Sphingolipid Metabolomics, Hangzhou, 310053, China. lpqin@zcmu.edu.cn.

Funding

National Natural Science Foundation of China No. 82073956Zhejiang Chinese Medical University Research Foundation 2020ZG23Zhejiang Chinese Medical University Research Foundation 2021ZR08Zhejiang Province Traditional Chinese Medicine Science and Technology Project 2023ZF087Zhejiang Provincial Medicine and Health Science and Technology Plan Project 2022490995Zhejiang Provincial Natural Science Foundation of China LGC20B050010Zhejiang Provincial Natural Science Foundation of China LQ22H270004Zhejiang students' technology and innovation program 2022R410A025
6 · The paper itself

Abstract

The quantitative analysis of near-infrared spectroscopy in traditional Chinese medicine has still deficiencies in the selection of the measured indexes. Then Paeoniae Radix Alba is one of the famous "Eight Flavors of Zhejiang" herbs, however, it lacks the pharmacodynamic support, and cannot reflect the quality of Paeoniae Radix Alba accurately and reasonably. In this study, the spectrum-effect relationship of the anti-inflammatory activity of Paeoniae Radix Alba was established. Then based on the obtained bioactive component groups, the genetic algorithm, back propagation neural network, was combined with near-infrared spectroscopy to establish calibration models for the content of the bioactive components of Paeoniae Radix Alba. Finally, three bioactive components, paeoniflorin, 1,2,3,4,6-O-pentagalloylglucose, and benzoyl paeoniflorin, were successfully obtained. Their near-infrared spectroscopy content models were also established separately, and the validation sets results showed the coefficient of determination (R

Indexed as

Drugs, Chinese HerbalSpectroscopy, Near-InfraredGlycosidesNeural Networks, ComputerPaeoniaPlant ExtractsQuality ControlDrugs, Chinese HerbalGlycosidespeoniflorinpeony root extractPlant ExtractsBack propagation neural network (BPNN)Genetic algorithm (GA)Near-infrared spectroscopy (NIRS)Paeoniae Radix Alba (PRA)Spectrum–effect relationship

Identifiers

PMID37037970

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.