Evidence map›Paper›PMID 37037844›Full record

ArticleScientific reports2023

Effects of adipose derived stem cells pretreated with resveratrol on sciatic nerve regeneration in rats.

Ziqiang Zhang, Mengyu Zhang, Yingying Sun, Monan Li, Chenhao Chang, Weiqi Liu, Xuemin Zhu, Lan Wei, Fengyun Wen, Yumei Liu

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ziqiang Zhang *College of Animal Science and Technology, Henan University of Science and Technology, Luoyang, 471000, Henan, China.
Mengyu Zhang *College of Animal Science and Technology, Henan University of Science and Technology, Luoyang, 471000, Henan, China.
Yingying Sun *College of Animal Science and Technology, Henan University of Science and Technology, Luoyang, 471000, Henan, China.
Monan LiThe School of Materials Science and Engineering, Henan University of Science and Technology, Luoyang, 471000, Henan, China.
Chenhao ChangCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang, 471000, Henan, China.
Weiqi LiuCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang, 471000, Henan, China.
Xuemin ZhuCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang, 471000, Henan, China.
Lan WeiCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang, 471000, Henan, China.
Fengyun WenCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang, 471000, Henan, China.
Yumei LiuCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang, 471000, Henan, China. yumeiliu@haust.edu.cn.
Henan University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adipose derived stem cells (ADSCs) are popular in regenerative medicine due to their easy availability, low immunogenicity and lack of controversy regarding their ethical debate use. Although ADSCs can repair nerve damage, the oxidative microenvironment of damaged tissue can induce apoptosis of transplanted stem cells, which weakens the therapeutic efficacy of ADSCs. Resveratrol (Res) is a type of natural polyphenol compound that regulates the proliferation, senescence and differentiation of stem cells. Therefore, we investigated whether incubation of ADSCs with Res improves their to promote peripheral nerve regeneration. ADSCs were cultured in vitro and treated with H

Indexed as

Hydrogen PeroxideSciatic NerveAdipose TissueAnimalsbcl-2-Associated X ProteinCaspase 3Nerve RegenerationRatsRats, Sprague-DawleyResveratrolStem Cellsbcl-2-Associated X ProteinCaspase 3Hydrogen PeroxideResveratrol

Identifiers

PMID37037844
PMCPMC10085980
OpenAlexW4363650813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.