ArticleThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation2023
Donation after circulatory death heart procurement strategy impacts utilization and outcomes of concurrently procured abdominal organs.
Article in The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 36 citations in OpenAlex.
- Reperfusion Strategies in Donation After Circulatory Death Heart Transplantation: An Up-to-Date Narrative Review.Journal of clinical medicine · 2026Review
- Heart transplantation graft survival following donation after circulatory death via thoracoabdominal normothermic regional perfusion.JHLT open · 2026Article
- Increasing adoption of donation after circulatory death in high-risk heart transplant recipients: Insights into current practices in the United States.JTCVS open · 2026Article
- Early and Mid-Term Results of Solid Organ Transplantation After Circulatory Death: A 4-Year Single Centre Experience.Medicina (Kaunas, Lithuania) · 2025Article
- Thoracoabdominal Normothermic Regional Perfusion: Real-world Experience and Outcomes of DCD Liver Transplantation.Transplantation direct · 2025Article
- Thoracoabdominal Normothermic Regional Perfusion and Donation After Circulatory Death Lung Use.JAMA network open · 2025Article
- Impact of dual thoracic recovery from circulatory death donors on heart and lung transplant outcomes.The Journal of thoracic and cardiovascular surgery · 2025Article
- A scoping review of the legal and ethical challenges with the use of normothermic regional perfusion in controlled donation after circulatory determination of death from 2005 to 2023.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025Article
- Heart Transplantation and Donation After Circulatory Death in Children. A Review of the Technological, Logistical and Ethical Framework.Transplant international : official journal of the European Society for Organ Transplantation · 2025Review
- The Rapidly Evolving Landscape of DCD Heart Transplantation.Current cardiology reports · 2024Review
- Post-transplant survival after normothermic regional perfusion versus direct procurement and perfusion in donation after circulatory determination of death in heart transplantation.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2024Observational
- Donation after circulatory death significantly reduces waitlist times while not changing post-heart transplant outcomes: A United Network for Organ Sharing Analysis.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2024Article
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Authors and funding
14 authors at 3 institutions in 1 country.
Funding
Abstract
introductionThe impact of donation after circulatory death (DCD) heart procurement techniques on the utilization and outcomes of concurrently procured DCD livers and kidneys remains unclear.
methodsUsing the United Network for Organ Sharing database, we identified 246 DCD donors whose heart was procured using direct procurement and ex-situ machine perfusion and 128 DCD donors whose heart was procured using in-situ thoracoabdominal normothermic regional perfusion (12/2019-03/2022). We evaluated the transplantation rate of concurrently procured DCD livers and kidneys (defined as the number of organs transplanted/total number of organs available for procurement) and their post-transplant outcomes.
resultsThe transplantation rate of concurrently procured DCD livers was higher with in-situ perfusion compared to direct procurement (67.1% vs 56.5%, p = 0.045). After excluding pediatric, multiorgan, and repeat transplant recipients, there was no difference in 6-month liver graft failure rate (direct procurement 0.9% vs in-situ perfusion 0%, p > 0.99). Recipients of kidneys procured with in-situ perfusion had less delayed graft function (11.3% vs 41.5%, p < 0.0001) shorter length of stay, and lower serum creatinine at discharge (both p < 0.05). Six-month recipient survival in the direct procurement and in-situ perfusion group were similar after DCD liver and kidney transplantation (p = 0.24 and 0.79 respectively).
conclusionsCompared to direct procurement, DCD heart procurement with in-situ thoracoabdominal normothermic regional perfusion was associated with increased utilization of DCD livers and a lower incidence of delayed graft function in concurrently procured DCD kidneys. Broader implementation of DCD heart transplantation must maximize the transplant potential of concurrently procured abdominal organs and ensure their successful outcomes.
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