Evidence map›Paper›PMID 37037620›Full record

Observational studyBMJ open2023

One-year major adverse cardiovascular events among same-day discharged patients after primary percutaneous coronary intervention at a tertiary care cardiac centre in Karachi, Pakistan: a prospective observational study.

Jehangir Ali Shah, Rajesh Kumar, Bashir Ahmed Solangi, Kamran Ahmed Khan, Tarique Ahmed, Sanam Khowaja, Gulzar Ali, Mehwish Zehra, Jawaid Akbar Sial, Musa Karim and 2 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Jehangir Ali ShahDepartment of Cardiology, National Institute of Cardiovascular Diseases, Karachi, Sindh, Pakistan dr_shah_80@hotmail.com.ORCID 0000-0003-3624-2418
Rajesh KumarDepartment of Cardiology, National Institute of Cardiovascular Diseases, Karachi, Sindh, Pakistan.ORCID 0000-0002-6580-7193
Bashir Ahmed SolangiDepartment of Cardiology, National Institute of Cardiovascular Diseases, Karachi, Sindh, Pakistan.
Kamran Ahmed KhanDepartment of Cardiology, National Institute of Cardiovascular Diseases, Karachi, Sindh, Pakistan.
Tarique AhmedDepartment of Cardiology, National Institute of Cardiovascular Diseases, Karachi, Sindh, Pakistan.
Sanam KhowajaDepartment of Cardiology, National Institute of Cardiovascular Diseases, Karachi, Sindh, Pakistan.
Gulzar AliDepartment of Cardiology, National Institute of Cardiovascular Diseases, Karachi, Sindh, Pakistan.
Mehwish ZehraDepartment of Medicine, Jinnah Post Graduate Medical Centre, Karachi, Pakistan.
Jawaid Akbar SialDepartment of Cardiology, National Institute of Cardiovascular Diseases, Karachi, Sindh, Pakistan.
Musa KarimDepartment of Cardiology, National Institute of Cardiovascular Diseases, Karachi, Sindh, Pakistan.
Tahir SaghirDepartment of Cardiology, National Institute of Cardiovascular Diseases, Karachi, Sindh, Pakistan.
Nadeem QamarDepartment of Cardiology, National Institute of Cardiovascular Diseases, Karachi, Sindh, Pakistan.
National Institute of Cardiovascular Diseases · PKJinnah Postgraduate Medical Center · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveKnowledge regarding the short-term outcomes after same-day discharge (SDD) post primary percutaneous coronary intervention (PCI) is lacking. In this study, we evaluated 1-year major adverse cardiovascular events (MACE) among SDD patients after primary PCI.

design1-year follow-up analysis of a subset of patients from an existing prospective cohort study.

settingTertiary care cardiac hospital in Karachi, Pakistan.

participantsConsecutive patients, from August 2019 to July 2020, with ST segment elevation myocardial infarction who had undergone primary PCI with SDD (within 24 hours) after the procedure by the treating physician and with at least one successful follow-up up to 1 year. OUTCOME MEASURE: Cumulative MACE during follow-up at the intervals of 1 week, 1 month, 6 months and 1 year.

results489 patients were included, with a gender distribution of 83.2% (407) male patients and a mean age of 54.58±10.85 years. Overall MACE rate during the mean follow-up duration of 326.98±76.71 days was 10.8% (53), out of which 26.4% (14/53) events occurred within 6 months of discharge and the remaining 73.6% (39/53) occurred between 6 months and 1 year. MACE was significantly higher among patients with a Zwolle Risk Score (ZRS) ≥4 at baseline, with an incidence rate of 21.9% (16/73) vs 8.9% (37/416; p=0.001) in patients with ZRS≤3 (relative risk 2.88 (95% CI 1.5 to 5.5)).

conclusionA significant burden of short-term MACE was identified among SDD patients after primary PCI; most of these events occurred after 6 months of SDD, mainly among patients with ZRS≥4. A systematic risk assessment based on risk stratification modalities such ZRS could be a viable option for SDD patients with primary PCI.

Indexed as

Percutaneous Coronary InterventionST Elevation Myocardial InfarctionAdultAgedHumansMaleMiddle AgedPakistanPatient DischargeProspective StudiesTertiary Health CareTreatment Outcomeadult cardiologycoronary heart diseasecoronary interventionischaemic heart diseasemyocardial infarction

Identifiers

PMID37037620
PMCPMC10111899
OpenAlexW4363673474

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.