Evidence map›Paper›PMID 37037491›Full record

ArticleCancer communications (London, England)2023

Advanced precision modeling reveals divergent responses of hepatocellular carcinoma to combinatorial immunotherapy.

Jinping Liu, Lan Cheng, Hilana El-Mekkoussi, Charles-Antoine Assenmacher, Michelle Y Y Lee, Danielle R Jaffe, Kaisha Garvin-Darby, Ashleigh Morgan, Elisabetta Manduchi, Jonathan Schug and 1 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer communications (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jinping LiuDepartment of Genetics and Center for Molecular Studies in Digestive and Liver Disease, University of Pennsylvania, Philadelphia, PA, USA.
Lan ChengInstitute for Diabetes, Obesity and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Hilana El-MekkoussiDepartment of Genetics and Center for Molecular Studies in Digestive and Liver Disease, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0001-5561-4358
Charles-Antoine AssenmacherDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Michelle Y Y LeeDepartment of Genetics and Center for Molecular Studies in Digestive and Liver Disease, University of Pennsylvania, Philadelphia, PA, USA.
Danielle R JaffeDepartment of Genetics and Center for Molecular Studies in Digestive and Liver Disease, University of Pennsylvania, Philadelphia, PA, USA.
Kaisha Garvin-DarbyDepartment of Genetics and Center for Molecular Studies in Digestive and Liver Disease, University of Pennsylvania, Philadelphia, PA, USA.
Ashleigh MorganDepartment of Genetics and Center for Molecular Studies in Digestive and Liver Disease, University of Pennsylvania, Philadelphia, PA, USA.
Elisabetta ManduchiDepartment of Genetics and Center for Molecular Studies in Digestive and Liver Disease, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-4110-3714
Jonathan SchugDepartment of Genetics and Center for Molecular Studies in Digestive and Liver Disease, University of Pennsylvania, Philadelphia, PA, USA.
Klaus H KaestnerDepartment of Genetics and Center for Molecular Studies in Digestive and Liver Disease, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-1228-021X

Funding

VIRAL VECTOR COREP30DK019525 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI MITCHELL A. LAZAR · 1986 to 2026
$48.3M
TRANSGENIC AND CHIMERIC MOUSE COREP30DK050306 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI Ken Hashigiwa Cadwell · 1997 to 2026
$32.5M
Innovative Genetic Approaches to Enhance Liver Repopulation and Reduce Cancer Risk and ProgressionR01CA249929 · NCI · UNIVERSITY OF PENNSYLVANIA · PI KAESTNER, KLAUS H · 2020 to 2024
$2.7M
NCI NIH HHS R01 CA249929NIDDK NIH HHS P30 DK019525NIDDK NIH HHS P30 DK050306
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsHumansImmunotherapy

Identifiers

PMID37037491
PMCPMC10259666

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.