Evidence map›Paper›PMID 37037430›Full record

ArticleThe American journal of tropical medicine and hygiene2023

Multi-Cause Calibration of Verbal Autopsy-Based Cause-Specific Mortality Estimates of Children and Neonates in Mozambique.

Brian Gilbert, Jacob Fiksel, Emily Wilson, Henry Kalter, Almamy Kante, Aveika Akum, Dianna Blau, Quique Bassat, Ivalda Macicame, Eduardo Samo Gudo and 4 more

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Article
  9. Addressing the Gaps in Mortality Data: A Case for National Mortality Surveillance.The American journal of tropical medicine and hygiene · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Brian GilbertDepartment of Biostatistics, Johns Hopkins University, Baltimore, Maryland.
Jacob FikselDepartment of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania.
Emily WilsonDepartment of International Health, Johns Hopkins University, Baltimore, Maryland.
Henry KalterDepartment of International Health, Johns Hopkins University, Baltimore, Maryland.
Almamy KanteDepartment of International Health, Johns Hopkins University, Baltimore, Maryland.
Aveika AkumDepartment of International Health, Johns Hopkins University, Baltimore, Maryland.
Dianna BlauCenter for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia.
Quique BassatISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Ivalda MacicameInstituto Nacional de Saúde (INS), Maputo, Mozambique.
Eduardo Samo GudoInstituto Nacional de Saúde (INS), Maputo, Mozambique.
Robert BlackDepartment of International Health, Johns Hopkins University, Baltimore, Maryland.
Scott ZegerDepartment of Biostatistics, Johns Hopkins University, Baltimore, Maryland.
Agbessi AmouzouDepartment of International Health, Johns Hopkins University, Baltimore, Maryland.
Abhirup DattaDepartment of Biostatistics, Johns Hopkins University, Baltimore, Maryland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Countrywide Mortality Surveillance for Action platform is collecting verbal autopsy (VA) records from a nationally representative sample in Mozambique. These records are used to estimate the national and subnational cause-specific mortality fractions (CSMFs) for children (1-59 months) and neonates (1-28 days). Cross-tabulation of VA-based cause-of-death (COD) determination against that from the minimally invasive tissue sampling (MITS) from the Child Health and Mortality Prevention project revealed important misclassification errors for all the VA algorithms, which if not accounted for will lead to bias in the estimates of CSMF from VA. A recently proposed Bayesian VA-calibration method is used that accounts for this misclassification bias and produces calibrated estimates of CSMF. Both the VA-COD and the MITS-COD can be multi-cause (i.e., suggest more than one probable COD for some of the records). To fully use this probabilistic COD data, we use the multi-cause VA calibration. Two different computer-coded VA algorithms are considered-InSilicoVA and EAVA-and the final CSMF estimates are obtained using an ensemble calibration that uses data from both the algorithms. The calibrated estimates consistently offer a better fit to the data and reveal important changes in the CSMF for both children and neonates in Mozambique after accounting for VA misclassification bias.

Indexed as

DeathAutopsyBayes TheoremCalibrationCause of DeathChildHumansInfant, NewbornMozambique

Identifiers

PMID37037430
PMCPMC10160855

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.