Evidence map›Paper›PMID 37037424›Full record

SynthesisThe American journal of tropical medicine and hygiene2023

Exploring the Mosquito-Arbovirus Network: A Survey of Vector Competence Experiments.

Binqi Chen, Amy R Sweeny, Velen Y Wu, Rebecca C Christofferson, Gregory Ebel, Anna C Fagre, Emily Gallichotte, Rebekah C Kading, Sadie J Ryan, Colin J Carlson

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in The American journal of tropical medicine and hygiene, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
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  7. Ten quick tips to build a Model Life Cycle.PLoS computational biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Binqi ChenCenter for Global Health Science and Security, Georgetown University Medical Center, Washington, District of Columbia.
Amy R SweenyCenter for Global Health Science and Security, Georgetown University Medical Center, Washington, District of Columbia.
Velen Y WuCenter for Global Health Science and Security, Georgetown University Medical Center, Washington, District of Columbia.
Rebecca C ChristoffersonDepartment of Pathobiological Sciences, Louisiana State University, Baton Rouge, Louisiana.
Gregory EbelCenter for Vector-borne Infectious Diseases, Colorado State University, Fort Collins, Colorado.
Anna C FagreCenter for Vector-borne Infectious Diseases, Colorado State University, Fort Collins, Colorado.
Emily GallichotteCenter for Vector-borne Infectious Diseases, Colorado State University, Fort Collins, Colorado.
Rebekah C KadingCenter for Vector-borne Infectious Diseases, Colorado State University, Fort Collins, Colorado.
Sadie J RyanDepartment of Geography, University of Florida, Gainesville, Florida.
Colin J CarlsonCenter for Global Health Science and Security, Georgetown University Medical Center, Washington, District of Columbia.
Colorado State University · USGeorgetown University · USCenter for Global Health · USGeorgetown University Medical Center · USLouisiana State University · USUniversity of KwaZulu-Natal · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arboviruses receive heightened research attention during major outbreaks or when they cause unusual or severe clinical disease, but they are otherwise undercharacterized. Global change is also accelerating the emergence and spread of arboviral diseases, leading to time-sensitive questions about potential interactions between viruses and novel vectors. Vector competence experiments help determine the susceptibility of certain arthropods to a given arbovirus, but these experiments are often conducted in real time during outbreaks, rather than with preparedness in mind. We conducted a systematic review of reported mosquito-arbovirus competence experiments, screening 570 abstracts to arrive at 265 studies testing in vivo arboviral competence. We found that more than 90% of potential mosquito-virus combinations are untested in experimental settings and that entire regions and their corresponding vectors and viruses are undersampled. These knowledge gaps stymie outbreak response and limit attempts to both build and validate predictive models of the vector-virus network.

Indexed as

AedesArbovirusesArbovirus InfectionsCulicidaeAnimalsDisease OutbreaksHumansMosquito Vectors

Identifiers

PMID37037424
PMCPMC10160896
OpenAlexW4363650483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.