Evidence map›Paper›PMID 37037391›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2023

Disseminated mycobacterial infections after tumor necrosis factor inhibitor use, revealing inborn errors of immunity.

Jacqueline D Squire, Claudia R Libertin, Harry Powers, Jared Nelson, Lisa Brumble, Federico R Laham, Anahita Agharahimi, Alexandra F Freeman, Jennifer W Leiding

Abstract readCase Reports
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
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  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jacqueline D SquireDivision of Pulmonary, Allergy, and Sleep Medicine, Mayo Clinic, Jacksonville, USA. Electronic address: squire.jacqueline@mayo.edu.
Claudia R LibertinDivision of Infectious Diseases, Mayo Clinic, Jacksonville, USA.
Harry PowersDivision of Infectious Diseases, Mayo Clinic, Jacksonville, USA.
Jared NelsonDivision of Infectious Diseases, Mayo Clinic, Jacksonville, USA.
Lisa BrumbleDivision of Infectious Diseases, Mayo Clinic, Jacksonville, USA.
Federico R LahamPediatric Infectious Disease and Immunology Arnold Palmer Hospital for Children at Orlando Health, Orlando, USA.
Anahita AgharahimiLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
Alexandra F FreemanLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
Jennifer W LeidingPediatric Infectious Disease and Immunology Arnold Palmer Hospital for Children at Orlando Health, Orlando, USA; Division of Allergy and Immunology, Department of Pediatrics, Johns Hopkins University, Baltimore, USA.

Funding

Primary Immune Deficiency ClinicZIAAI001247 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI FREEMAN, ALEXANDRA · 2019 to 2025
$8.7M
Intramural NIH HHS ZIA AI001247
6 · The paper itself

Abstract

Tumor necrosis factor-a inhibitors can be associated with increased risk of infections, particularly reactivation of latent tuberculosis or nontuberculous mycobacterium (NTM). However, because disseminated NTM is rare, inborn errors of immunity should be considered. We present three patients with disseminated NTM after tumor necrosis factor-a inhibitor use who were found to have inborn errors of immunity.

Indexed as

Mycobacterium Infections, NontuberculousTumor Necrosis Factor InhibitorsHumansNontuberculous MycobacteriaTumor Necrosis Factor-alphaTumor Necrosis Factor-alphaTumor Necrosis Factor InhibitorsImmunodeficiencyInborn errors of immunityInfliximabMycobacteriaTNF inhibitor

Identifiers

PMID37037391
PMCPMC10339357

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.